Understanding snake venom pharmacokinetics is essential for developing risk assessment
strategies and determining the optimal dose and timing of antivenom required to bind all …

An understanding of snake venom pharmacokinetics is essential for determining clinical
outcomes of envenoming and developing therapeutic approaches to the treatment of …

The most abundant protein families in viper venoms are Snake Venom Metalloproteases
(SVMPs), Snake Venom Serine Proteases (SVSPs) and Phospholipases (PLA2s). These are …

Snakebite envenomation is responsible for over 100,000 deaths and 400,000 cases of
disability annually, most of which are preventable through access to safe and effective …

Toxinology of snake venoms: the Malaysian context Page 25 Toxinology of Snake Venoms:
The Malaysian Context 1 Choo Hock Tan and Nget Hong Tan Contents Introduction …

Objectives Understanding the time course of venom exposure in snakebite patients is
important for the optimisation of treatment including antivenom dose and timing. We aimed …

In recent years it has become possible to design snakebite antivenoms with diverse
pharmacokinetic properties. Owing to the pharmacokinetic variability of venoms, the choice …

Several in vitro investigations have demonstrated that anticoagulant effects of
fibrinogenolytic snake venom metalloproteinases have been abrogated in human plasma by …

Snake venom is comprised of a combination of different proteins and peptides with a wide
range of molecular weights and different disposition processes inherent to each compound …

The treatment protocol of antivenom in snake envenomation remains largely empirical,
partly due to the insufficient knowledge of the pharmacokinetics of snake venoms and the …