Update on viral gene therapy clinical trials for retinal diseases
In 2001, the first large animal was successfully treated with a gene therapy that restored its
vision. Lancelot, the Briard dog that was treated, suffered from a human childhood blindness …
vision. Lancelot, the Briard dog that was treated, suffered from a human childhood blindness …
[HTML][HTML] Visual hallucinations originating in the retinofugal pathway under clinical and psychedelic conditions
Z Tipado, KPC Kuypers, B Sorger… - European …, 2024 - Elsevier
Psychedelics like LSD (Lysergic acid diethylamide) and psilocybin are known to modulate
perceptual modalities due to the activation of mostly serotonin receptors in specific cortical …
perceptual modalities due to the activation of mostly serotonin receptors in specific cortical …
A demonstration of cone function plasticity after gene therapy in achromatopsia
M Farahbakhsh, EJ Anderson, RO Maimon-Mor… - Brain, 2022 - academic.oup.com
Recent advances in regenerative therapy have placed the treatment of previously incurable
eye diseases within arms' reach. Achromatopsia is a severe monogenic heritable retinal …
eye diseases within arms' reach. Achromatopsia is a severe monogenic heritable retinal …
Structural differences across multiple visual cortical regions in the absence of cone function in congenital achromatopsia
Most individuals with congenital achromatopsia (ACHM) carry mutations that affect the
retinal phototransduction pathway of cone photoreceptors, fundamental to both high acuity …
retinal phototransduction pathway of cone photoreceptors, fundamental to both high acuity …
[HTML][HTML] fMRI and gene therapy in adults with CNGB3 mutation
EJ Anderson, TM Dekker, M Farahbakhsh, N Hirji… - Brain Research …, 2024 - Elsevier
Achromatopsia is an inherited retinal disease that affects 1 in 30,000–50,000 individuals
and is characterised by an absence of functioning cone photoreceptors from birth. This …
and is characterised by an absence of functioning cone photoreceptors from birth. This …
Achromatopsia—Visual Cortex Stability and Plasticity in the Absence of Functional Cones
Purpose: Achromatopsia is a rare inherited disorder rendering retinal cone photoreceptors
nonfunctional. As a consequence, the sizable foveal representation in the visual cortex is …
nonfunctional. As a consequence, the sizable foveal representation in the visual cortex is …
[PDF][PDF] Achromatopsia-limits to visual cortex plasticity in the absence of functional cones
PURPOSE. Achromatopsia is a rare inherited disorder rendering retinal cone
photoreceptors nonfunctional. As a consequence, the sizable foveal representation in the …
photoreceptors nonfunctional. As a consequence, the sizable foveal representation in the …
Vision restoration: Little red booster
AR Wade - Current Biology, 2023 - cell.com
Vision restoration: Little red booster: Current Biology Skip to Main Content Advertisement
Current Biology This journal offers authors two options (open access or subscription) to publish …
Current Biology This journal offers authors two options (open access or subscription) to publish …
Update on gene therapies in pediatric ophthalmology
D Bremond-Gignac, MP Robert, A Daruich - Archives de Pédiatrie, 2023 - Elsevier
Rare eye diseases encompass a broad spectrum of genetic anomalies with or without
additional extraocular manifestations. Genetic eye disorders in pediatric patients often lead …
additional extraocular manifestations. Genetic eye disorders in pediatric patients often lead …
Achromatopsie
B Käsmann-Kellner, MB Hoffmann - Die Ophthalmologie, 2023 - Springer
Zusammenfassung Die Achromatopsie oder Stäbchenmonochromasie ist eine kongenitale
autosomal-rezessiv vererbte Netzhautdystrophie, die zu Zapfenfehlfunktion mit verminderter …
autosomal-rezessiv vererbte Netzhautdystrophie, die zu Zapfenfehlfunktion mit verminderter …