Phospholipids play multiple roles in cells by establishing the permeability barrier for cells
and cell organelles, by providing the matrix for the assembly and function of a wide variety of …

The unifying feature of all proteins that are transported out of the cytoplasm of gram-negative
bacteria by the general secretory pathway (GSP) is the presence of a long stretch of …

SecA, the peripheral subunit of E. coli preprotein translocase, alternates between a
membrane inserted and a deinserted state as part of the catalytic cycle of preprotein …

Protein transport across the endoplasmic reticulum membrane can occur by two pathways, a
co-and a post-translational one. In both cases, polypeptides are first targeted to translocation …

A list of currently identified gene products of Escherichia coli is given, together with a
bibliography that provides pointers to the literature on each gene product. A scheme to …

The SecA subunit of E. coli preprotein translocase promotes protein secretion during cycles
of membrane insertion and deinsertion at SecYEG. This process is regulated both by …

Six putative ATP‐binding motifs of SecA protein were altered by oligonucleotide‐directed
mutagenesis to try to define the ATP‐binding regions of this multifunctional protein. The …

The SecD protein is one of the components that has been suggested from genetic studies to
be involved in the protein secretion across the cytoplasmic membrane of Escherichia coli …

The ATPase SecA mediates post-translational translocation of precursor proteins through
the SecYEG channel of the bacterial inner membrane. We show that SecA, up to now …

Using C-terminal deletion mutations in secA, we localized the previously proposed
(Breukink, E., Keller, RCA, and de Kruijff, B.(1993), FEBS Lett. 331, 19-24) second lipid …