Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease predominantly affecting
upper and lower motor neurons. The disease leads to relentlessly progressive weakness of …

Amyotrophic lateral sclerosis (ALS) is a devastating, uniformly lethal degenerative disorder
of motor neurons that overlaps clinically with frontotemporal dementia (FTD). Investigations …

Amyotrophic lateral sclerosis (ALS) is a severe neurodegenerative condition characterized
by loss of motor neurons in the brain and spinal cord. Expansions of a hexanucleotide …

Amyotrophic lateral sclerosis (ALS) is a severe progressive neurodegenerative disease. The
cause is unknown, but genetic abnormalities have been identified in subjects with familial …

Genome sequencing of both sporadic and familial patients of Amyotrophic Lateral Sclerosis
(ALS) has led to the identification of new genes that are both contributing and causative in …

Amyotrophic lateral sclerosis (ALS) is a heterogeneous group of neurological conditions
which have in common the progressive degeneration of upper and lower motor neurons …

The genetic architecture of amyotrophic lateral sclerosis (ALS) is being increasingly
understood. In this far-reaching review, we examine what is currently known about ALS …

Amyotrophic lateral sclerosis (ALS) is a fatal late onset neurological disorder characterized
by motor neuron degeneration in the primary motor cortex, brainstem and spinal cord. The …

There is a strong genetic contribution to Amyotrophic lateral sclerosis (ALS) risk, with
heritability estimates of up to 60%. Both Mendelian and small effect variants have been …

Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disorder,
caused by the degeneration of upper and lower motor neurons for which there is no truly …