Biotechnology and in vitro culture as an alternative system for secondary metabolite production

M Mohaddab, Y El Goumi, M Gallo, D Montesano… - Molecules, 2022 - mdpi.com
Medicinal plants are rich sources of bioactive compounds widely used as medicaments,
food additives, perfumes, and agrochemicals. These secondary compounds are produced …

Plant hairy roots: Induction, applications, limitations and prospects

Y Zhu, X Zhu, Y Wen, L Wang, Y Wang, C Liao… - Industrial Crops and …, 2024 - Elsevier
Hairy roots (HRs) are highly branched adventitious roots generated by the infection of plants
with Agrobacterium rhizogenes. Due to the fast growth rate, genetic stability, strong …

Arachidin-1, a prenylated stilbenoid from peanut, enhances the anticancer effects of paclitaxel in triple-negative breast cancer cells

S Mohammadhosseinpour, A Weaver, M Sudhakaran… - Cancers, 2023 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is an aggressive type of cancer that
is challenging to treat due to the lack of hormonal receptors used to target cancer cells; due …

Elicitation of Stilbenes and Benzofuran Derivatives in Hairy Root Cultures of White Mulberry (Morus alba)

L Fang, AR Sharma, C Aniemena, K Roedel, F Henry… - Plants, 2022 - mdpi.com
Stilbene and benzofuran derivatives isolated from the root of white mulberry (Morus alba)
have shown various biological activities, including anti-inflammatory, antioxidant, and …

Effect of peanut stilbenoids, arachidin-1 and arachidin-3, on Streptococcus mutans growth and acid production

KB Reed, E Pruitt, KC Hansa Raj… - Natural Product …, 2024 - Taylor & Francis
In this study we evaluated the effect of prenylated peanut stilbenoids on the growth, biofilm
accumulation and acid production of the dental caries pathogen Streptococcus mutans. Prior …

[HTML][HTML] Production of Malheuran A, a Geranylated Flavonoid with Antimicrobial and Anti-Inflammatory Activities, in Hairy Root Cultures of Dalea purpurea

AR Sharma, G Gajurel, S Abdel-Karim, MA Alam… - Plants, 2025 - pmc.ncbi.nlm.nih.gov
Phenolic compounds, such as stilbenes and flavonoids, from Dalea spp. exhibit diverse
biological activities, including antimicrobial, anti-inflammatory, and cytotoxicity properties. To …

[HTML][HTML] Stilbene-rich extract increases the cytotoxic effects of paclitaxel in hormone receptor-positive and triple-negative breast cancer spheroids

S Mohammadhosseinpour, A Weaver… - Phytomedicine Plus, 2024 - Elsevier
Background Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer
that lacks three receptors commonly found in breast cancer cells. It is associated with high …

Integration of phenylalanine precursor feeding and elicitor treatment in concert with the cellulase-assisted extraction approach to improve stilbene compound …

C Tothong, C Pankaew, P Chayjarung… - Plant Cell, Tissue and …, 2023 - Springer
Abstract Trans-resveratrol, trans-arachidin-1 (Ara-1), and trans-arachidin-3 (Ara-3) are major
stilbene compounds found in elicited peanut hairy root culture and exert diverse potential …

Soybean Hairy Root Transformation for the Analysis of Gene Function

J Lin, D Wi, M Ly, MA Jahan, S Pullano… - JoVE (Journal of …, 2023 - jove.com
Soybean (Glycine max) is a valuable crop in agriculture that has thousands of industrial
uses. Soybean roots are the primary site of interaction with soil-borne microbes that form …