Animal models of heart failure with preserved ejection fraction (HFpEF): from metabolic pathobiology to drug discovery

S Gao, X Liu, T Li, L Chen, Y Feng, Y Wang… - Acta Pharmacologica …, 2024 - nature.com
Heart failure (HF) with preserved ejection fraction (HFpEF) is currently a preeminent
challenge for cardiovascular medicine. It has a poor prognosis, increasing mortality, and is …

Skeletal muscle mitochondrial respiration and exercise intolerance in patients with heart failure with preserved ejection fraction

L Scandalis, DW Kitzman, BJ Nicklas, M Lyles… - JAMA …, 2023 - jamanetwork.com
Importance The pathophysiology of exercise intolerance in patients with heart failure with
preserved ejection fraction (HFpEF) remains incompletely understood. Multiple lines of …

Locomotor and respiratory muscle abnormalities in HFrEF and HFpEF

N Mangner, EB Winzer, A Linke… - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Heart failure (HF) is a chronic and progressive syndrome affecting worldwide billions of
patients. Exercise intolerance and early fatigue are hallmarks of HF patients either with a …

[HTML][HTML] The 2022 On-site Padua Days on Muscle and Mobility Medicine hosts the University of Florida Institute of Myology and the Wellstone Center, March 30-April 3 …

HL Sweeney, S Masiero, U Carraro - European Journal of …, 2022 - ncbi.nlm.nih.gov
In the autumn of 2021, the 2022 Padua Days of Muscle and Mobility Medicine (PDM3) was
planned to be held from March 30 to April 2, 2022. Despite the fact that Coronavirus COVID …

Histological changes in skeletal muscle induced by heart failure in human patients and animal models: A scoping review

A Kaneguchi, N Sakitani, T Umehara - Acta Histochemica, 2024 - Elsevier
Objective This scoping review aimed to characterize the histological changes in skeletal
muscle after heart failure (HF) and to identify gaps in knowledge. Methods On April 03, 2024 …

Exercise training for patients with heart failure and preserved ejection fraction. A narrative review

G Caminiti, M Volterrani, F Iellamo… - … Archives for Chest …, 2024 - monaldi-archives.org
Heart failure with preserved ejection fraction (HFpEF) remains a significant global health
challenge, accounting for up to 50% of all heart failure cases and predominantly affecting …

Skeletal Muscle Mitochondrial Respiration and Exercise Intolerance in Patients With Heart Failure With Preserved Ejection Fraction

PP Battery - hypertension, 2023 - jamanetwork.com
OBJECTIVE To evaluate the associations of skeletal muscle mitochondrial function using
respirometric analysis of biopsied muscle fiber bundles from patients with HFpEF with …