Illuminating the brain: advances and perspectives in optoelectronics for neural activity monitoring and modulation

S Xu, M Momin, S Ahmed, A Hossain… - Advanced …, 2023 - Wiley Online Library
Optogenetic modulation of brain neural activity that combines optical and electrical modes in
a unitary neural system has recently gained robust momentum. Controlling illumination …

The prediction-error hypothesis of schizophrenia: new data point to circuit-specific changes in dopamine activity

SJ Millard, CE Bearden, KH Karlsgodt… - …, 2022 - nature.com
Schizophrenia is a severe psychiatric disorder affecting 21 million people worldwide. People
with schizophrenia suffer from symptoms including psychosis and delusions, apathy …

Black phosphorus flake-enabled wireless neuromodulation for epilepsy treatment

D Yang, Q Ren, J Nie, Y Zhang, H Wu, Z Chang… - Nano Letters, 2023 - ACS Publications
Epilepsy is a prevalent and severe neurological disorder and generally requires prolonged
electrode implantation and tether brain stimulation in refractory cases. However, implants …

Network models to enhance the translational impact of cross-species studies

JK Brynildsen, K Rajan, MX Henderson… - Nature Reviews …, 2023 - nature.com
Neuroscience studies are often carried out in animal models for the purpose of
understanding specific aspects of the human condition. However, the translation of findings …

[HTML][HTML] Optogenetics for visual restoration: from proof of principle to translational challenges

M Lindner, MJ Gilhooley, S Hughes… - Progress in retinal and …, 2022 - Elsevier
Degenerative retinal disorders are a diverse family of diseases commonly leading to
irreversible photoreceptor death, while leaving the inner retina relatively intact. Over recent …

Closed-loop optogenetic control of the dynamics of neural activity in non-human primates

B Zaaimi, M Turnbull, A Hazra, Y Wang… - Nature biomedical …, 2023 - nature.com
Electrical neurostimulation is effective in the treatment of neurological disorders, but
associated recording artefacts generally limit its applications to open-loop stimuli. Real-time …

Nanotechnology enables novel modalities for neuromodulation

X Yang, E McGlynn, R Das, SP Paşca, B Cui… - Advanced …, 2021 - Wiley Online Library
Neuromodulation is of great importance both as a fundamental neuroscience research tool
for analyzing and understanding the brain function, and as a therapeutic avenue for treating …

Parvalbumin role in epilepsy and psychiatric comorbidities: from mechanism to intervention

LD Godoy, T Prizon, MT Rossignoli, JP Leite… - Frontiers in Integrative …, 2022 - frontiersin.org
Parvalbumin is a calcium-binding protein present in inhibitory interneurons that play an
essential role in regulating many physiological processes, such as intracellular signaling …

Drug addiction: from bench to bedside

J Cheron, A Kerchove d'Exaerde - Translational Psychiatry, 2021 - nature.com
Drug addiction is responsible for millions of deaths per year around the world. Still, its
management as a chronic disease is shadowed by misconceptions from the general public …

Rhodopsins: an excitingly versatile protein species for research, development and creative engineering

WJ de Grip, S Ganapathy - Frontiers in Chemistry, 2022 - frontiersin.org
The first member and eponym of the rhodopsin family was identified in the 1930s as the
visual pigment of the rod photoreceptor cell in the animal retina. It was found to be a …