The classical studies of nicotine by Langley at the turn of the 20th century introduced the
concept of a “receptive substance,” from which the idea of a “receptor” came to light …

In recent years, neonicotinoids have been the fastest‐growing class of insecticides in
modern crop protection, with widespread use against a broad spectrum of sucking and …

In recent years, neonicotinoid insecticides have been the fastest growing class of
insecticides in modern crop protection, with widespread use against a broad spectrum of …

The past 30 years have witnessed a period of significant expansion in the use of
halogenated compounds in the field of agrochemical research and development. The …

Peptide therapeutics are acclaimed as a promising addition to the pharmaceutical arena,
and they continue to attract interest due to their high potency, bioavailability, and fewer …

Upon ligand binding at the subunit interfaces, the extracellular domain of the nicotinic
acetylcholine receptor undergoes conformational changes, and agonist binding …

The destruction of crops by invertebrate pests is a major threat against a background of a
continuously rising demand in food supply for a growing world population. Therefore …

Nicotinic acetylcholine receptors (nAChRs) are integral membrane proteins and prototypic
members of the ligand‐gated ion‐channel superfamily, which has precursors in the …

Neuronal nicotinic acetylcholine receptors (nAChRs) are prototypical cation-selective, ligand-
gated ion channels that mediate fast neurotransmission in the central and peripheral …

The crystal structure of the snake long α‐neurotoxin, α‐cobratoxin, bound to the pentameric
acetylcholine‐binding protein (AChBP) from Lymnaea stagnalis, was solved from good …