Contrasting roles for IgM and B-cell MHCII expression in Brucella abortus S19 vaccine-mediated efficacy against B. melitensis infection

MFN Abushahba, AS Dadelahi, B Ponzilacqua-Silva… - Msphere, 2024 - Am Soc Microbiol
Brucellosis, caused by the bacterium Brucella, poses a significant global threat to both
animal and human health. Although commercial live Brucella vaccines including S19, RB51 …

Serological Investigation for Brucella ceti in Cetaceans from the Northwestern Mediterranean Sea

L Martino, M Cuvertoret-Sanz… - Animals: an Open …, 2024 - pmc.ncbi.nlm.nih.gov
Simple Summary Brucella ceti is a marine bacterium that causes neurological, reproductive
and skeletal disease in free-ranging cetaceans. Its zoonotic potential and importance for …

Vaccine-Elicited Antibodies Restrict Glucose Availability to Control Brucella Infection

B Ponzilacqua-Silva, AS Dadelahi… - The Journal of …, 2024 - academic.oup.com
The impact of vaccine-induced immune responses on host metabolite availability has not
been well studied. Here we show that prior vaccination alters the metabolic profile of mice …

The challenge of managing ischemic stroke in brucellosis: a case report

L Chen, X Lin, X Cai, S Zeng, Y Yuan, Z Huang… - Frontiers in …, 2024 - frontiersin.org
A 64-year-old woman was admitted to the hospital for sudden weakness in one of her left
limbs. The patient was diagnosed with acute ischemic stroke (IS) of undetermined cause …

Immune checkpoint blockade in experimental bacterial infections

NL Henriksen, PØ Jensen, LK Jensen - Journal of Infection - journalofinfection.com
Immune checkpoint inhibitors designed to reinvigorate immune responses suppressed by
cancer cells have revolutionized cancer therapy. Similarities in immune dysregulation …