[HTML][HTML] Anxiety, depression, and the microbiome: a role for gut peptides

G Lach, H Schellekens, TG Dinan, JF Cryan - Neurotherapeutics, 2018 - Elsevier
The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …

[HTML][HTML] Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders

N Singewald, C Schmuckermair, N Whittle… - Pharmacology & …, 2015 - Elsevier
Pathological fear and anxiety are highly debilitating and, despite considerable advances in
psychotherapy and pharmacotherapy they remain insufficiently treated in many patients with …

Remodeling of microbiota gut-brain axis using psychobiotics in depression

MSK Palepu, MP Dandekar - European journal of pharmacology, 2022 - Elsevier
Depression is a multifaceted psychiatric disorder mainly orchestrated by dysfunction of
neuroendocrine, neurochemical, immune, and metabolic systems. The interconnection of …

Serotonin in fear conditioning processes

EP Bauer - Behavioural brain research, 2015 - Elsevier
This review describes the latest developments in our understanding of how the serotonergic
system modulates Pavlovian fear conditioning, fear expression and fear extinction. These …

Comparative density of CCK-and PV-GABA cells within the cortex and hippocampus

PD Whissell, JD Cajanding, N Fogel… - Frontiers in …, 2015 - frontiersin.org
Cholecystokinin (CCK)-and parvalbumin (PV)-expressing neurons constitute the two major
populations of perisomatic GABAergic neurons in the cortex and the hippocampus. As CCK …

The role of serotonin in memory: interactions with neurotransmitters and downstream signaling

M Seyedabadi, G Fakhfouri, V Ramezani… - Experimental brain …, 2014 - Springer
Abstract Serotonin, or 5-hydroxytryptamine (5-HT), is found to be involved in many
physiological or pathophysiological processes including cognitive function. Seven distinct …

Serotonergic regulation of prefrontal cortical circuitries involved in cognitive processing: a review of individual 5-HT receptor mechanisms and concerted effects of 5 …

SC Leiser, Y Li, AL Pehrson, E Dale… - ACS chemical …, 2015 - ACS Publications
It has been known for several decades that serotonergic neurotransmission is a key
regulator of cognitive function, mood, and sleep. Yet with the relatively recent discoveries of …

Systematic review, structural analysis, and new theoretical perspectives on the role of serotonin and associated genes in the etiology of psychopathy and sociopathy

BO Yildirim, JJL Derksen - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
Since its theoretical inception, psychopathy has been considered by philosophers,
clinicians, theorists, and empirical researchers to be substantially and critically explained by …

Corticotropin-releasing factor-related peptides, serotonergic systems, and emotional behavior

JH Fox, CA Lowry - Frontiers in neuroscience, 2013 - frontiersin.org
Corticotropin-releasing factor (CRF) is a 41-amino acid neuropeptide that is involved in
stress-related physiology and behavior, including control of the hypothalamic-pituitary …

5-HT systems: emergent targets for memory formation and memory alterations

A Meneses - Reviews in the Neurosciences, 2013 - degruyter.com
Drugs acting through 5-hydroxytryptamine (serotonin or 5-HT) systems modulate memory
and its alterations, although the mechanisms involved are poorly understood. 5-HT drugs …