While the amino acids, enzymes and hormones are chiral, chirality plays significant role in
the life of plants, animals, as well as the human being. Chirality of molecules is important in …

Chirality plays a vital role in the lives of humans, plants, and animals because various
proteins, amino acids, hormones, enzymes are chiral in nature. It is important in different …

Breast cancer leads to the highest mortality among women resulting in a major clinical
burden. Multidrug therapy is more efficient in such patients compared to monodrug therapy …

The chiral separations of small peptides is an important challenge in the biological and
medical sciences, because different stereoisomers of chiral drugs can often possess …

Bortezomib (BTZ) and dasatinib (DA) are two substantial anti-cancer agents with side effects
on the human body. In this research, we fabricated a novel electrochemical sensor modified …

Most cancer patients rarely benefit from monodrug therapy because of both cancer
complexity and tumor environment. One of the main reasons for this failure is insufficient …

Aim & Objective: This study evaluates the potential of combining paclitaxel (PTX) and
bortezomib (BTZ) for breast cancer therapy. Materials & Methods: The nanoformulation was …

Bortezomib (BTZ) is a proteasome inhibitor as approved by US FDA for the treatment of
multiple myeloma. It exhibits significant anti-cancer properties, against solid tumors; but …

In this paper, X-ray diffraction (XRD), differential scanning calorimetry (DSC), broadband
dielectric (BDS), and Fourier transform infrared (FTIR) spectroscopy supported by molecular …

Ixazomib is the only orally active proteasome inhibitor used in clinical practice as an
anticancer drug. The novel, rapid UHPLC-UV assay for ixazomib was developed and …