Heterometallic cages: synthesis and applications

LK Moree, LAV Faulkner, JD Crowley - Chemical Society Reviews, 2024 - pubs.rsc.org
High symmetry metallosupramolecular architectures (MSAs) have been exploited for a
range of applications including molecular recognition, catalysis and drug delivery. Recently …

Anticancer agents based on metal organic cages

D Sun, X Feng, X Zhu, Y Wang, J Yang - Coordination Chemistry Reviews, 2024 - Elsevier
Cancer is the second leading cause of death worldwide, even though various anticancer
strategies have been developed. The rapid development of nanotechnologies has …

Synthesis of 177Lu-Labeled, Somatostatin-2 Receptor-Targeted Metalla-Assemblies: Challenges in the Design of Supramolecular Radiotherapeutics

S Deiser, M Drexler, G Moreno-Alcántar, M Irl… - Inorganic …, 2023 - ACS Publications
Self-assembled supramolecular coordination complexes (SCCs) hold promise for
biomedical applications in cancer therapy, although their potential in the field of nuclear …

The multifaceted roles of MnL2n cages in catalysis

Z Ashbridge, JNH Reek - Nature Synthesis, 2024 - nature.com
Metal–organic cages are versatile supramolecular architectures, fulfilling various distinct
roles in the mediation of catalysed chemical reactions. M n L2 n cages have become …

Assembling a new generation of radiopharmaceuticals with supramolecular theranostics

G Moreno-Alcántar, M Drexler, A Casini - Nature Reviews Chemistry, 2024 - nature.com
Supramolecular chemistry has been used to tackle some of the major challenges in modern
science, including cancer therapy and diagnosis. Supramolecular platforms provide …

Tackling Severe Neutrophilic Inflammation in Airway Disorders with Functionalized Nanosheets

Z Tu, Y Zhu, W Gao, M Liu, Y Wei, C Xu, Y Xiao… - ACS …, 2024 - ACS Publications
Severe airway inflammatory disorders impose a significant societal burden, and the
available treatments are unsatisfactory. High levels of neutrophil extracellular trap (NET) and …

A dynamic covalent approach to [Pt n L 2n] 2n+ cages

QVC van Hilst, AC Pearcy, D Preston… - Chemical …, 2024 - pubs.rsc.org
A dynamic covalent approach was exploited to generate a family of homometallic [PtnL2n]
2n+ cage (predominantly [Pt2L4] 4+ systems) architectures. The family of platinum (II) …

Functional 2D Nanoplatforms Alleviate Eosinophilic Chronic Rhinosinusitis by Modulating Eosinophil Extracellular Trap Formation

Z Tu, M Liu, C Xu, Y Wei, T Lu, Y Xiao, H Li… - Advanced …, 2024 - Wiley Online Library
The therapeutic outcomes of patients with eosinophilic chronic rhinosinusitis (ECRS) remain
unsatisfactory, largely because the underlying mechanisms of eosinophilic inflammation are …

A Golden Touch in the Design of Multifunctional Porphyrin Metallacages: Host–Guest Chemistry for Drug-Target Interactions

T Rodríguez-Prieto, D Wragg, N Heiduk… - CCS …, 2024 - chinesechemsoc.org
The use of three-dimensional self-assembled metallacages (MCgs) as multimodal drug
platforms holds great promise. However, the synthesis of MCgs with increased complexity …

[HTML][HTML] Metaparticles: Computationally engineered nanomaterials with tunable and responsive properties

M Paesani, IM Ilie - The Journal of Chemical Physics, 2024 - pubs.aip.org
In simulations, particles are traditionally treated as rigid platforms with variable sizes,
shapes, and interaction parameters. While this representation is applicable for rigid core …