Vitamin D in neurological diseases

D Plantone, G Primiano, C Manco, S Locci… - International journal of …, 2022 - mdpi.com
Vitamin D may have multiple effects on the nervous system and its deficiency can represent
a possible risk factor for the development of many neurological diseases. Recent studies are …

[HTML][HTML] The role of hydrogen therapy in Alzheimer's disease management: Insights into mechanisms, administration routes, and future challenges

J He, F Liu, T Xu, J Ma, H Yu, J Zhao, Y Xie… - Biomedicine & …, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder predominantly
affecting the elderly. While conventional pharmacological therapies remain the primary …

Customized Intranasal Hydrogel Delivering Methylene Blue Ameliorates Cognitive Dysfunction against Alzheimer's Disease

Y Liu, Y Tan, G Cheng, Y Ni, A Xie, X Zhu… - Advanced …, 2024 - Wiley Online Library
The accumulation of hyperphosphorylated tau protein aggregates is a key pathogenic event
in Alzheimer's disease (AD) and induces mitochondrial dysfunction and reactive oxygen …

An ongoing journey of chalcone analogues as single and multi-target ligands in the field of Alzheimer's disease: A review with structural aspects

P Sharma, M Singh - Life Sciences, 2023 - Elsevier
Alzheimer's disease (AD) is a chronic and irreversible neurodegenerative disorder with
progressive dementia and cognitive impairment. AD poses severe health challenge in …

Update on new trend and progress of the mechanism of polysaccharides in the intervention of Alzheimer's disease, based on the new understanding of relevant …

X Zhang, L Lin, H Li, W Xia, Q Liu, X Zhou… - International Journal of …, 2022 - Elsevier
Abstract Alzheimer's disease (AD), a neurodegenerative disease with insidious onset and
progressive progression, is the main type of dementia. Currently, there is no specific cure for …

Parental History of Memory Impairment and β-Amyloid in Cognitively Unimpaired Older Adults

M Seto, TJ Hohman, EC Mormino, KV Papp… - JAMA …, 2024 - jamanetwork.com
Importance Studies have suggested that maternal history of late-onset Alzheimer disease,
but not paternal, predisposes individuals to higher brain β-amyloid (Aβ) burden, reduced …

Poly (ADP-ribose) polymerase: an overview of mechanistic approaches and therapeutic opportunities in the management of stroke

P Tiwari, H Khan, TG Singh, AK Grewal - Neurochemical Research, 2022 - Springer
Stroke is one of the leading causes of morbidity and mortality accompanied by blood supply
loss to a particular brain area. Several mechanistic approaches such as inhibition of poly …

Mitochondrial dynamics related neurovascular approaches in cerebral ischemic injury

H Khan, AK Grewal, TG Singh - Mitochondrion, 2022 - Elsevier
Mitochondria are double-membrane organelles that provide the majority of a cell's energy.
Furthermore, mitochondria are involved in various cellular biological activities, including …

Scrutinizing the therapeutic potential of PROTACs in the management of Alzheimer's disease

S Bhatia, M Singh, T Singh, V Singh - Neurochemical research, 2023 - Springer
Finding an effective cure for Alzheimer's disease has eluded scientists despite intense
research. The disease is a cause of suffering for millions of people worldwide and is …

Aerobic exercise combined with chlorogenic acid exerts neuroprotective effects and reverses cognitive decline in Alzheimer's disease model mice (APP/PS1) via the …

D Shi, Z Hao, W Qi, F Jiang, K Liu, X Shi - Frontiers in Aging …, 2023 - frontiersin.org
Alzheimer's disease (AD) is a prevalent neurodegenerative disease account for 60–80% of
the total number of people with dementia, but its treatment and prevention strategies are still …