Bone plates play a vital role in bone fracture healing by providing the necessary mechanical
fixation for fracture fragments through modulating biomechanical microenvironment adjacent …

Bone is a mineralized conjunctive tissue, with a unique trauma healing capability. However,
the replacement or regeneration of lost bone is not always successful and becomes more …

Bone is a hard-connective tissue composed of matrix, cells and bioactive factors with a
hierarchical structure, where the matrix is mainly composed of type I collagen and …

The local sustained release of bioactive substances are attracting increasing attention in
bone tissue engineering, which is beneficial to bone tissue formation and helps to improve …

Biomimetic scaffolds have been a growing demand in bone tissue engineering. Owing to the
performance shortcomings of single natural or synthetic polymer, nano hydroxyapatite …

Osteoporosis is defined as a systemic skeletal disease characterized by low bone mass and
microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility …

Current bioceramic scaffolds for critical-size bone defects are still facing various challenges
such as the poor capability of self-resorption, vascularization and osteogenesis. Herein, a …

Abstract Development of biomimetic scaffolds represents a promising direction in bone
tissue engineering. In this study, we designed a two-step process to prepare a type of …

The periosteum plays a crucial role in both bone development and the healing process of
bone fractures. However, few studies have focused on developing artificial periosteum due …

Significant efforts have been made to develop a suitable biocompatible scaffold for bone
tissue engineering. In this work, a chitosan-graft-poly (acrylic acid-co-acrylamide) …