Mesenchymal stem cells (MSC) are present in all organs and tissues. Several studies have
shown the therapeutic potential effect of MSC or their derived products. However, the …

Long-term exposure to a diabetic environment leads to changes in bone metabolism and
impaired bone micro-architecture through a variety of mechanisms on molecular and …

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that affects more
than 44 million people worldwide. Despite the high disease burden, there is no effective …

Abstract More than 2.1 million age-related fractures occur in the United States annually,
resulting in an immense socioeconomic burden. Importantly, the age-related deterioration of …

Maxillofacial hard tissue defects caused by trauma or infection often affect craniofacial
function. Taking the natural hard tissue structure as a template, constructing an engineered …

Around 40% of the population will suffer at some point in their life a disease involving tissue
loss or an inflammatory or autoimmune process that cannot be satisfactorily controlled with …

Simple Summary Aging and frailty are complex processes implicating multifactorial
mechanisms, which demand for new therapeutic strategies against their devastating effects …

Inflammatory bowel diseases (IBD) are an example of chronic diseases affecting 40% of the
population, which involved tissue damage and an inflammatory process not satisfactorily …

Acute respiratory distress syndrome (ARDS) represents a current challenge for medicine
due to its incidence, morbidity and mortality and, also, the absence of an optimal treatment …

Background Breast cancer is the most frequently diagnosed cancer and a common cause of
cancer-related death in women. It is well recognized that obesity is associated with an …