Trillions of microbes live symbiotically in the host, specifically in mucosal tissues such as the
gut. Recent advances in metagenomics and metabolomics have revealed that the gut …

Organ crosstalk is a complex biological communication between distal organs mediated via
cellular, soluble, and neurohormonal actions, based on a two-way pathway. The …

White matter injury (WMI) is thought to be a major contributor to long-term cognitive
dysfunctions after traumatic brain injury (TBI). This damage occurs partly due to apoptotic …

The connection between dysbiosis of the gut microbiome and diseases and injuries of the
brain has attracted considerable interest in recent years. Interestingly, antibiotic-induced …

Acute care management of traumatic brain injury is focused on the prevention and reduction
of secondary insults such as hypotension, hypoxia, intracranial hypertension, and …

TBI is a leading cause of death and disability in young people and older adults worldwide.
There is no gold standard treatment for TBI besides surgical interventions and symptomatic …

Traumatic brain injury (TBI) is a chronic and debilitating disease, associated with a high risk
of psychiatric and neurodegenerative diseases. Despite significant advancements in …

Background Traumatic brain injury (TBI) is one of the most serious types of trauma and
imposes a heavy social and economic burden on healthcare systems worldwide. The …

Background Traumatic brain injury (TBI) leads to acute gastrointestinal dysfunction and
mucosal damage, resulting in feeding intolerance. Ccr2+ monocytes are crucial immune …

Alzheimer's disease (AD) is characterized by cognitive decline and neuropathology
including amyloid beta (Aβ) plaques and neurofibrillary tangles (tau). Factors initiating or …