Where chemocatalysis meets biocatalysis: In water

H Gröger, F Gallou, BH Lipshutz - Chemical Reviews, 2022 - ACS Publications
Chemoenzymatic catalysis, by definition, involves the merging of sequential reactions using
both chemocatalysis and biocatalysis, typically in a single reaction vessel. A major …

Expanding the synthetic toolbox through metal–enzyme cascade reactions

S González-Granda, J Albarrán-Velo… - Chemical …, 2023 - ACS Publications
The combination of metal-, photo-, enzyme-, and/or organocatalysis provides multiple
synthetic solutions, especially when the creation of chiral centers is involved. Historically …

One-pot chemo-and photo-enzymatic linear cascade processes

JM Carceller, KS Arias, MJ Climent, S Iborra… - Chemical Society …, 2024 - pubs.rsc.org
The combination of chemo-and photocatalyses with biocatalysis, which couples the flexible
reactivity of the photo-and chemocatalysts with the highly selective and environmentally …

Engineering and emerging applications of artificial metalloenzymes with whole cells

M Wittwer, U Markel, J Schiffels, J Okuda, DF Sauer… - Nature Catalysis, 2021 - nature.com
The field of artificial metalloenzymes (ArMs) is rapidly growing and ArMs are attracting
increasing attention, for example, in the fields of biosensing and drug therapy. Protein …

Artificial metalloenzymes

T Vornholt, F Leiss-Maier, WJ Jeong… - Nature Reviews …, 2024 - nature.com
The development of artificial metalloenzymes (ArMs) aims to expand the capabilities of
enzymatic catalysis, most notably towards new reaction mechanisms. Frequently, ArMs …

Recent advances in (chemo) enzymatic cascades for upgrading bio-based resources

Y Zhou, S Wu, UT Bornscheuer - Chemical Communications, 2021 - pubs.rsc.org
Developing (chemo) enzymatic cascades is very attractive for green synthesis, because they
streamline multistep synthetic processes. In this Feature Article, we have summarized the …

High-Yield Synthesis of Enantiopure 1,2-Amino Alcohols from l-Phenylalanine via Linear and Divergent Enzymatic Cascades

ML Corrado, T Knaus, U Schwaneberg… - … Process Research & …, 2022 - ACS Publications
Enantiomerically pure 1, 2-amino alcohols are important compounds due to their biological
activities and wide applications in chemical synthesis. In this work, we present two …

[HTML][HTML] Recent developments in compartmentalization of chemoenzymatic cascade reactions

D Kracher, R Kourist - Current Opinion in Green and Sustainable Chemistry, 2021 - Elsevier
Uniting the unparalleled stereoselectivity of enzymes with the efficiency of chemical catalysis
offers high product yields and atom economy while limiting downstream processing efforts …

Design of artificial enzymes: insights into protein scaffolds.

S Hanreich, E Bonandi, I Drienovská - Chembiochem: a European …, 2022 - europepmc.org
The design of artificial enzymes has emerged as a promising tool for the generation of
potent biocatalysts able to promote new-to-nature reactions with improved catalytic …

Current Status of Amine Dehydrogenases: From Active Site Architecture to Diverse Applications Across a Broad Substrate Spectrum

V Tseliou, MF Masman, T Knaus, FG Mutti - ChemCatChem, 2024 - Wiley Online Library
Amine dehydrogenases (AmDHs) are NAD (P) H‐dependent oxidoreductases that catalyze
the reductive amination between carbonyl compounds and ammonia as the amine donor …