Infectious keratitis: A review

M Cabrera‐Aguas, P Khoo… - Clinical & Experimental …, 2022 - Wiley Online Library
Globally, infectious keratitis is the fifth leading cause of blindness. The main predisposing
factors include contact lens wear, ocular injury and ocular surface disease. Staphylococcus …

Fungal keratitis: A review of clinical presentations, treatment strategies and outcomes

N Sharma, B Bagga, D Singhal, R Nagpal, A Kate… - The ocular …, 2022 - Elsevier
Infectious keratitis is a significant cause of corneal blindness worldwide. Although less
prevalent in the developed world, cases of fungal keratitis account for almost half of all …

Targeting herpes simplex virus with CRISPR–Cas9 cures herpetic stromal keratitis in mice

D Yin, S Ling, D Wang, Y Dai, H Jiang, X Zhou… - Nature …, 2021 - nature.com
Herpes simplex virus type 1 (HSV-1) is a leading cause of infectious blindness. Current
treatments for HSV-1 do not eliminate the virus from the site of infection or latent reservoirs in …

A rapid corneal healing microneedle for efficient ocular drug delivery

H Shi, J Zhou, Y Wang, Y Zhu, D Lin, L Lei, S Vakal… - Small, 2022 - Wiley Online Library
Fungal keratitis (FK) remains a serious clinical problem worldwide, so the ultimate goal of
the treatment is to develop a minimally invasive, safe, and effective method for ocular drug …

[HTML][HTML] Mycotic keratitis—a global threat from the filamentous fungi

JJ Hoffman, MJ Burton, A Leck - Journal of Fungi, 2021 - mdpi.com
Mycotic or fungal keratitis (FK) is a sight-threatening disease, caused by infection of the
cornea by filamentous fungi or yeasts. In tropical, low and middle-income countries, it …

A deep learning approach in diagnosing fungal keratitis based on corneal photographs

MT Kuo, BWY Hsu, YK Yin, PC Fang, HY Lai, A Chen… - Scientific reports, 2020 - nature.com
Fungal keratitis (FK) is the most devastating and vision-threatening microbial keratitis, but
clinical diagnosis a great challenge. This study aimed to develop and verify a deep learning …

Using slit-lamp images for deep learning-based identification of bacterial and fungal keratitis: model development and validation with different convolutional neural …

N Hung, AKY Shih, C Lin, MT Kuo, YS Hwang, WC Wu… - Diagnostics, 2021 - mdpi.com
In this study, we aimed to develop a deep learning model for identifying bacterial keratitis
(BK) and fungal keratitis (FK) by using slit-lamp images. We retrospectively collected slit …

Recent Advances in Diagnosis and Treatment Approaches in Fungal Keratitis: A Narrative Review

LA Ghenciu, AC Faur, SL Bolintineanu, MC Salavat… - Microorganisms, 2024 - mdpi.com
Fungal keratitis represents a potentially sight-threatening infection associated with poor
prognosis, as well as financial burden. Novel diagnostic methods include polymerase-chain …

Management of filamentous fungal keratitis: a pragmatic approach

JJ Hoffman, S Arunga, AHA Mohamed Ahmed, VH Hu… - Journal of Fungi, 2022 - mdpi.com
Filamentous fungal infections of the cornea known as filamentous fungal keratitis (FK) are
challenging to treat. Topical natamycin 5% is usually first-line treatment following the results …

Pharmacologic therapy of mycotic keratitis

P Sahay, D Singhal, R Nagpal, PK Maharana… - Survey of …, 2019 - Elsevier
Mycotic keratitis continues to be an important cause of corneal blindness, especially in
tropical and subtropical countries. The prognosis is poor compared with many other forms of …