An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L.

K Shahane, M Kshirsagar, S Tambe, D Jain, S Rout… - Pharmaceuticals, 2023 - mdpi.com
Calendula officinalis Linn.(CO) is a popular medicinal plant from the plant kingdom's
Asteraceae family that has been used for millennia. This plant contains flavonoids …

Galantamine based novel acetylcholinesterase enzyme inhibitors: A molecular modeling design approach

LB Silva, EFB Ferreira, Maryam, JM Espejo-Román… - Molecules, 2023 - mdpi.com
Acetylcholinesterase (AChE) enzymes play an essential role in the development of
Alzheimer's disease (AD). Its excessive activity causes several neuronal problems …

Identification of a novel dual inhibitor of acetylcholinesterase and butyrylcholinesterase: in vitro and in silico studies

RBM de Almeida, DB Barbosa, MR do Bomfim… - Pharmaceuticals, 2023 - mdpi.com
The enhancement of cholinergic functions via acetylcholinesterase (AChE) and
butyrylcholinesterase (BuChE) inhibition is considered a valuable therapeutic strategy for …

Alarmins and inflammatory aspects related to snakebite envenomation

JP Zuliani - Toxicon, 2023 - Elsevier
Snakebite envenoming is characterized by the injection of a mixture of proteins/toxins
present in venom following the bite of a venomous snake. The toxins have potent bioactivity …

Synthesis of new hydrazones using a biodegradable catalyst, their biological evaluations and molecular modeling studies (Part-II)

SN Mali, A Pandey - Journal of Computational Biophysics and …, 2022 - World Scientific
Hydrazones typically have an azomethine '–NHN= CH group'which is crucial for varieties of
pharmacological activities. In this study, we have synthesized a set of 15 new hydrazones …

Identification of potential mutational hotspots in serratiopeptidase to address its poor pH tolerance issue

A Dhiman, R Purohit - Journal of Biomolecular Structure and …, 2023 - Taylor & Francis
Serratiopeptidase is the multifunctionality metalloendopeptidase extensively employed in
biopharmaceutical and industrial biotechnology. Despite its poor pH tolerance …

Exploring the chemical composition, in vitro and in silico study of the anticandidal properties of annonaceae species essential oils from the Amazon

MM Cascaes, SH Marques da Silva, MS de Oliveira… - PLoS …, 2023 - journals.plos.org
Chemical composition of the essential oils (EOs) from the leaves of five Annonaceae
species found in the amazon region was analyzed by Gas chromatography coupled to mass …

First Report on the Chemical Composition, Antioxidant Capacity, and Preliminary Toxicity to Artemia salina L. of Croton campinarensis Secco, A. Rosário & PE Berry …

LS da Costa, ÂAB de Moraes, JN Cruz, SN Mali… - Antioxidants, 2022 - mdpi.com
Croton campinarensis Secco, A. Rosário & PE Berry is an aromatic species recently
discovered in the Amazon region. This study first reports the chemical profile, antioxidant …

Analysis of the Impact of Ethanol Extract of Calendula officinalis L. on Human Fibroblast Cell Cultures Using the PANsys 3000 Device for Breeding and Visualization …

A Nowak-Terpiłowska, I Nowak, A Feliczak-Guzik… - Life, 2023 - mdpi.com
Calendula officinalis L. promotes wound healing and might be effective in gingival fibroblast
stimulation. The influence of different concentrations of Calendula officinalis L. ethanol …

Naja naja snake venom-induced local toxicities in mice is by inflammasome activation

MB Nandana, M Bharatha, BS Vishwanath, R Rajaiah - Toxicon, 2024 - Elsevier
Snake bite envenomation causes tissue damage resulting in acute and chronic inflammatory
responses. Inflammasome activation is one of the factors involved in tissue damage in a …