Primary acquired nasolacrimal duct obstruction, or PANDO, is a common adult lacrimal
drainage disorder. The current treatment modality of dacryocystorhinostomy to bypass the …

Diabetes mellitus is a major public health issue that affected 537 million people worldwide in
2021, a number that is only expected to increase in the upcoming decade. Diabetes is a …

Background Although stimulating autophagy caused by UV has been widely demonstrated
in skin cells to exert cell protection, it remains unknown the cellular events in UVA-treated …

Background: Organophosphate esters (OPEs) are flame retardants and plasticizers used in
consumer products. OPEs are found ubiquitously throughout the environment with high …

Background Hereditary angioedema (HAE) is a rare genetic disease that leads to recurrent
episodes of swelling and pain caused by uncontrolled plasma kallikrein (PKa) activity …

Solute-linked cotransporter, SLC4A11, a member of the bicarbonate transporter family, is an
electrogenic H+ transporter activated by NH3 and alkaline pH. Although SLC4A11 does not …

Autophagy is a catabolic self-degradative pathway that promotes the degradation and
recycling of intracellular material through the lysosomal compartment. Although first believed …

The cornea and covering tear film are together the 'objective lens' of the eye through which
80% of light is refracted. Despite exposure to a physically harsh and at times infectious or …

The transparent ocular lens in the anterior chamber of the eye is responsible for fine
focusing of light onto the retina. The lens is entirely cellular with bulk of the tissue composed …

Recent studies from Slc4a11−/− mice have identified glutamine-induced mitochondrial
dysfunction as a significant contributor toward oxidative stress, impaired lysosomal function …