[HTML][HTML] Unfolding a chordate developmental program, one cell at a time: invariant cell lineages, short-range inductions and evolutionary plasticity in ascidians

P Lemaire - Developmental biology, 2009 - Elsevier
Ascidians were historically the first metazoans in which experimental embryology was
carried out. These early works by Chabry and Conklin [Chabry, L., 1887. Embryologie …

Genetic and Genomic Toolbox of the Chordate Ciona intestinalis

A Stolfi, L Christiaen - Genetics, 2012 - academic.oup.com
The experimental malleability and unique phylogenetic position of the sea squirt Ciona
intestinalis as part of the sister group to the vertebrates have helped establish these marine …

Migratory neuronal progenitors arise from the neural plate borders in tunicates

A Stolfi, K Ryan, IA Meinertzhagen, L Christiaen - Nature, 2015 - nature.com
The neural crest is an evolutionary novelty that fostered the emergence of vertebrate
anatomical innovations such as the cranium and jaws. During embryonic development …

[HTML][HTML] Sequential activation of apical and basolateral contractility drives ascidian endoderm invagination

K Sherrard, F Robin, P Lemaire, E Munro - Current Biology, 2010 - cell.com
Background Epithelial invagination is a fundamental morphogenetic behavior that
transforms a flat cell sheet into a pit or groove. Previous studies of invagination have focused …

Tissue-specific genome editing in Ciona embryos by CRISPR/Cas9

A Stolfi, S Gandhi, F Salek, L Christiaen - Development, 2014 - journals.biologists.com
The CRISPR/Cas9 system has ushered in a new era of targeted genetic manipulations.
Here, we report the use of CRISPR/Cas9 to induce double-stranded breaks in the genome …

Contact area–dependent cell communication and the morphological invariance of ascidian embryogenesis

L Guignard, UM Fiúza, B Leggio, J Laussu, E Faure… - Science, 2020 - science.org
INTRODUCTION Within each animal species, embryonic development is highly
reproducible, ensuring the faithful production of a complex organism with precisely arranged …

Sequential contraction and exchange of apical junctions drives zippering and neural tube closure in a simple chordate

H Hashimoto, FB Robin, KM Sherrard, EM Munro - Developmental cell, 2015 - cell.com
Unidirectional zippering is a key step in neural tube closure that remains poorly understood.
Here, we combine experimental and computational approaches to identify the mechanism …

A framework for the establishment of a cnidarian gene regulatory network for “endomesoderm” specification: the inputs of ß-catenin/TCF signaling

E Röttinger, P Dahlin, MQ Martindale - PLoS genetics, 2012 - journals.plos.org
Understanding the functional relationship between intracellular factors and extracellular
signals is required for reconstructing gene regulatory networks (GRN) involved in complex …

Reiterative recombination for the in vivo assembly of libraries of multigene pathways

LM Wingler, VW Cornish - Proceedings of the National …, 2011 - National Acad Sciences
The increasing sophistication of synthetic biology is creating a demand for robust, broadly
accessible methodology for constructing multigene pathways inside of the cell. Due to the …

Automated high-throughput mapping of promoter-enhancer interactions in zebrafish embryos

J Gehrig, M Reischl, É Kalmár, M Ferg, Y Hadzhiev… - Nature …, 2009 - nature.com
Zebrafish embryos offer a unique combination of high-throughput capabilities and the
complexity of the vertebrate animal for a variety of phenotypic screening applications …