This review adds the bilin-binding phytochromes to the Chemical Reviews thematic issue “Optogenetics and Photopharmacology”. The work is structured into two parts. We first …
Y Zhou, D Kong, X Wang, G Yu, X Wu, N Guan… - Nature …, 2022 - nature.com
Optogenetic technologies have transformed our ability to precisely control biological processes in time and space. Yet, current eukaryotic optogenetic systems are limited by …
T cells engineered to express chimeric antigen receptors (CARs) can recognize and engage with target cancer cells with redirected specificity for cancer immunotherapy. However, there …
K Lehtinen, MS Nokia, H Takala - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
Optogenetics, a field concentrating on controlling cellular functions by means of light- activated proteins, has shown tremendous potential in neuroscience. It possesses superior …
Abstract The Gram-positive bacterium Bacillus subtilis exhibits complex spatial and temporal gene expression signals. Although optogenetic tools are ideal for studying such processes …
X Zhao, H Gao, Y Wang, Z Wang, J Zhou - ACS Synthetic Biology, 2022 - ACS Publications
Phycocyanobilin (PCB) is a kind of light-harvesting pigment which naturally exists in algae and plays important roles in absorbing and transferring energy. Based on its antioxidant and …
The ability to manipulate expression of exogenous genes in particular regions of living organisms has profoundly transformed the way we study biomolecular processes involved in …
L Miao, J Zhang, B Huang, Z Zhang, S Wang… - Frontiers in …, 2022 - frontiersin.org
Chimeric antigen receptor (CAR)-T cell therapy has become one of the hot topics in tumor immunity research in recent years. Although CAR-T cell therapy is highly effective in treating …
M Blain-Hartung, NC Rockwell, MV Moreno… - Journal of Biological …, 2018 - ASBMB
Class III adenylyl cyclases generate the ubiquitous second messenger cAMP from ATP often in response to environmental or cellular cues. During evolution, soluble adenylyl cyclase …