Cyanobacteria are an evolutionarily and ecologically important group of prokaryotes. They
exist in diverse habitats, ranging from hot springs and deserts to glaciers and the open …

This review adds the bilin-binding phytochromes to the Chemical Reviews thematic issue
“Optogenetics and Photopharmacology”. The work is structured into two parts. We first …

Optogenetic technologies have transformed our ability to precisely control biological
processes in time and space. Yet, current eukaryotic optogenetic systems are limited by …

T cells engineered to express chimeric antigen receptors (CARs) can recognize and engage
with target cancer cells with redirected specificity for cancer immunotherapy. However, there …

Optogenetics, a field concentrating on controlling cellular functions by means of light-
activated proteins, has shown tremendous potential in neuroscience. It possesses superior …

Abstract The Gram-positive bacterium Bacillus subtilis exhibits complex spatial and temporal
gene expression signals. Although optogenetic tools are ideal for studying such processes …

Phycocyanobilin (PCB) is a kind of light-harvesting pigment which naturally exists in algae
and plays important roles in absorbing and transferring energy. Based on its antioxidant and …

The ability to manipulate expression of exogenous genes in particular regions of living
organisms has profoundly transformed the way we study biomolecular processes involved in …

Chimeric antigen receptor (CAR)-T cell therapy has become one of the hot topics in tumor
immunity research in recent years. Although CAR-T cell therapy is highly effective in treating …

Class III adenylyl cyclases generate the ubiquitous second messenger cAMP from ATP often
in response to environmental or cellular cues. During evolution, soluble adenylyl cyclase …