Phospholipids and cholesterol: Inducers of cancer multidrug resistance and therapeutic targets

J Kopecka, P Trouillas, AČ Gašparović, E Gazzano… - Drug resistance …, 2020 - Elsevier
Lipids, phospholipids and cholesterol in particular, are the predominant components of the
plasma membrane, wherein multidrug efflux transporters of the ATP-binding cassette (ABC) …

Mitochondrial membrane lipids in the regulation of bioenergetic flux

ST Decker, K Funai - Cell metabolism, 2024 - cell.com
Oxidative phosphorylation (OXPHOS) occurs through and across the inner mitochondrial
membrane (IMM). Mitochondrial membranes contain a distinct lipid composition, aided by …

Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis

JM Johnson, AD Peterlin, E Balderas, EG Sustarsic… - Science …, 2023 - science.org
Thermogenesis by uncoupling protein 1 (UCP1) is one of the primary mechanisms by which
brown adipose tissue (BAT) increases energy expenditure. UCP1 resides in the inner …

Important trends in UCP3 investigation

EE Pohl, A Rupprecht, G Macher, KE Hilse - Frontiers in Physiology, 2019 - frontiersin.org
Membrane uncoupling protein 3 (UCP3), a member of the mitochondrial uncoupling protein
family, was discovered in 1997. UCP3′ s properties, such as its high homology to other …

Antibacterial properties of citral against Staphylococcus aureus: From membrane damage to metabolic inhibition

J Dai, M Bai, C Li, W San Cheang, H Cui, L Lin - Food Bioscience, 2023 - Elsevier
Citral, a natural antimicrobial agent, has been found to induce severe membrane damage
resulting in bacterial death. Despite its effectiveness, there is a lack of in-depth research on …

[HTML][HTML] Ketogenic diets composed of long-chain and medium-chain fatty acids induce cardiac fibrosis in mice

F Sternberg, C Sternberg, A Dunkel, T Beikbaghban… - Molecular …, 2023 - Elsevier
Purpose Heart diseases are the leading cause of death worldwide. Metabolic interventions
via ketogenic diets (KDs) have been used for decades to treat epilepsy, and more recently …

Enzymatic and non-enzymatic detoxification of 4-hydroxynonenal: Methodological aspects and biological consequences

M Mol, L Regazzoni, A Altomare, G Degani… - Free Radical Biology …, 2017 - Elsevier
Hydroxynonenal (HNE), an electrophilic end-product deriving from lipid peroxidation,
undergoes a heterogeneous set of biotransformations including enzymatic and non …

[HTML][HTML] Uncoupling mechanism and redox regulation of mitochondrial uncoupling protein 1 (UCP1)

P Ježek, M Jabůrek, RK Porter - Biochimica et Biophysica Acta (BBA) …, 2019 - Elsevier
Brown adipose tissue (BAT) and brown in white (brite) adipose tissue, termed also beige
adipose tissue, are major sites of mammalian nonshivering thermogenesis. Mitochondrial …

The role of phosphatidylethanolamine adducts in modification of the activity of membrane proteins under oxidative stress

EE Pohl, O Jovanovic - Molecules, 2019 - mdpi.com
Reactive oxygen species (ROS) and their derivatives, reactive aldehydes (RAs), have been
implicated in the pathogenesis of many diseases, including metabolic, cardiovascular, and …

Versatile Synthesis of Symmetric and Unsymmetric Imines via Photoelectrochemical Catalysis: Application to N‐Terminal Modification of Phenylalanine

CW Chiang, HL Li, TJ Lin, HC Chen… - … A European Journal, 2023 - Wiley Online Library
A strategy that combines electrochemical synthesis and photoredox catalysis was reported
for the efficient synthesis of imines. This approach was demonstrated to be highly versatile in …