Repurposing sigma-1 receptor ligands for COVID-19 therapy?
JM Vela - Frontiers in Pharmacology, 2020 - frontiersin.org
Outbreaks of emerging infections, such as COVID-19 pandemic especially, confront health
professionals with the unique challenge of treating patients. With no time to discover new …
professionals with the unique challenge of treating patients. With no time to discover new …
Diabetes and coronavirus (SARS-CoV-2): Molecular mechanism of Metformin intervention and the scientific basis of drug repurposing
Coronavirus Disease 2019 (COVID-19), caused by a new strain of coronavirus called
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), was declared a …
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), was declared a …
Targeting lipid rafts as a strategy against coronavirus
M Sorice, R Misasi, G Riitano, V Manganelli… - Frontiers in Cell and …, 2021 - frontiersin.org
Lipid rafts are functional membrane microdomains containing sphingolipids, including
gangliosides, and cholesterol. These regions are characterized by highly ordered and tightly …
gangliosides, and cholesterol. These regions are characterized by highly ordered and tightly …
The novel insight of SARS-CoV-2 molecular biology and pathogenesis and therapeutic options
On December 31, 2019, a novel coronavirus, being the third highly infective CoV and named
as coronavirus disease 2019 (COVID-19) in the city of Wuhan, was announced by the World …
as coronavirus disease 2019 (COVID-19) in the city of Wuhan, was announced by the World …
Research advances on the role of lipids in the life cycle of human coronaviruses
C Ding, Y Chen, G Miao, Z Qi - Microorganisms, 2023 - mdpi.com
Coronaviruses (CoVs) are emerging pathogens with a significant potential to cause life-
threatening harm to human health. Since the beginning of the 21st century, three highly …
threatening harm to human health. Since the beginning of the 21st century, three highly …
[HTML][HTML] Coronaviruses, cholesterol and statins: Involvement and application for Covid-19
The infectious power of coronaviruses is dependent on cholesterol present in the
membranes of their target cells. Indeed, the virus enters the infected cell either by fusion or …
membranes of their target cells. Indeed, the virus enters the infected cell either by fusion or …
Molecular basis of COVID-19 pathogenesis and in silico studies of potential pharmacological treatment
E Lam Cabanillas, A León Risco… - Revista de la …, 2021 - inicib.urp.edu.pe
ABSTRACT COVID-19 is a disease caused by SARS-CoV-2, a virus that represents a
serious threat to global health. The objective of the article is to deepen into the structure of …
serious threat to global health. The objective of the article is to deepen into the structure of …
[HTML][HTML] A review on protective roles and potential mechanisms of metformin in diabetic patients diagnosed with COVID-19
ZD Kifle, AE Woldeyohanis, CA Demeke - Metabolism Open, 2021 - Elsevier
The novel coronavirus disease 2019 (COVID‐19), is currently the leading threat to public
health and a huge challenge to the healthcare systems across the globe and caused by …
health and a huge challenge to the healthcare systems across the globe and caused by …
iTRAQ-based proteomic study on monocyte cell model discovered an association of LAMP2 downregulation with HIV-1 latency
L Yin, Q Wang, S Liu, J Chen, Y Zhang, L Lu, H Lu… - Proteome Science, 2024 - Springer
Background Patients with immunodeficiency virus-1 (HIV-1) infection are challenging to be
cured completely due to the existence of HIV-1 latency reservoirs. However, the knowledge …
cured completely due to the existence of HIV-1 latency reservoirs. However, the knowledge …
[PDF][PDF] Quality of cold plasma treated casein peptide targeting SARS-coV2: an in-silico approach
S Dash, R Jaganmohan - 2022 - academia.edu
Raw cow milk being a highly nutritive but its contamination is one of the factors that has to be
considered. Thermal treatment is generally adopted for decontamination of milk but at the …
considered. Thermal treatment is generally adopted for decontamination of milk but at the …