Engineered bacteria-based living materials for biotherapeutic applications

R Omer, MZ Mohsin, A Mohsin, BS Mushtaq… - … in Bioengineering and …, 2022 - frontiersin.org
Future advances in therapeutics demand the development of dynamic and intelligent living
materials. The past static monofunctional materials shall be unable to meet the requirements …

Recent advances in bacteria‐based platforms for inflammatory bowel diseases treatment

J Lu, X Shen, H Li, J Du - Exploration, 2024 - Wiley Online Library
Inflammatory bowel disease (IBD) is a recurring chronic inflammatory disease. Current
treatment strategies are aimed at alleviating clinical symptoms and are associated with …

Facile synthesis of Cr-Co co-doped CdO nanowires for photocatalytic, antimicrobial, and supercapacitor applications

T Munawar, MN ur Rehman, MS Nadeem… - Journal of Alloys and …, 2021 - Elsevier
Abstract Pristine CdO and chromium (Cr)-cobalt (Co) co-doped CdO nanowires via a facile
co-precipitation protocol were synthesized and characterized with different analytical …

[HTML][HTML] Evidence of a myenteric plexus barrier and its macrophage-dependent degradation during murine colitis: implications in enteric neuroinflammation

D Dora, S Ferenczi, R Stavely, VE Toth… - Cellular and Molecular …, 2021 - Elsevier
Background & Aims Neuroinflammation in the gut is associated with many gastrointestinal
(GI) diseases, including inflammatory bowel disease. In the brain, neuroinflammatory …

Depletion of muscularis macrophages ameliorates inflammation-driven dysmotility in murine colitis model

S Ferenczi, F Mogor, P Takacs, T Kovacs, VE Toth… - Scientific Reports, 2023 - nature.com
Previously, the presence of a blood-myenteric plexus barrier and its disruption was reported
in experimentally induced colitis via a macrophage-dependent process. The aim of this …

Novel technologies to characterize and engineer the microbiome in inflammatory bowel disease

A Boix-Amorós, H Monaco, E Sambataro… - Gut …, 2022 - Taylor & Francis
We present an overview of recent experimental and computational advances in technology
used to characterize the microbiome, with a focus on how these developments improve our …

Sonogenetics-controlled synthetic designer cells for cancer therapy in tumor mouse models

T Gao, L Niu, X Wu, D Dai, Y Zhou, M Liu, K Wu… - Cell Reports …, 2024 - cell.com
Bacteria-based therapies are powerful strategies for cancer therapy, yet their clinical
application is limited by a lack of tunable genetic switches to safely regulate the local …

Microbiota-targeted therapies in inflammation resolution

F Strati, G Lattanzi, C Amoroso, F Facciotti - Seminars in Immunology, 2022 - Elsevier
Gut microbiota has been shown to systemically shape the immunological landscape,
modulate homeostasis and play a role in both health and disease. Dysbiosis of gut …

From probiotic chassis to modification strategies, control and improvement of genetically engineered probiotics for inflammatory bowel disease

Y Huang, S Peng, R Zeng, H Yao, G Feng… - Microbiological Research, 2024 - Elsevier
With the rising morbidity of inflammatory bowel disease (IBD) year by year, conventional
therapeutic drugs with systemic side effects are no longer able to meet the requirements of …

Genetically engineered microorganisms and their impact on human health

M Mahdizade Ari, L Dadgar, Z Elahi… - … Journal of Clinical …, 2024 - Wiley Online Library
The emergence of antibiotic‐resistant strains, the decreased effectiveness of conventional
therapies, and the side effects have led researchers to seek a safer, more cost‐effective …