Simple Summary Kidney cancer is a frequent malignant tumor that accounts for
approximately 5% of all cancer incidences. It affects both males and females, but males are …

Multiple studies have demonstrated the importance of androgen receptor (AR) splice
variants (SVs) in the progression of prostate cancer to the castration-resistant phenotype …

Kidney cancer is a common malignancy that constitutes around 5% of all cancer cases.
Males are twice as likely to acquire renal cell carcinoma (RCC) compared to females and …

Abstract Purpose Androgen receptors (ARs) are expressed on a variety of cell types, and AR
signaling plays an important role in tumor development and progression in several cancers …

Background: There is some evidence to suggest that endogenous levels of sex hormones
might influence the etiology of cancers of the pancreas, kidney, and brain, but epidemiologic …

Pediatric renal cell carcinomas (RCC) differ from their adult counterparts not only in
histologic subtypes but also in clinical characteristics and outcome. However, the underlying …

Type 1 iodothyronine deiodinase (DIO1) contributes to deiodination of 3, 5, 3', 5'-tetraiodo-L-
thyronine (thyroxine, T4) yielding of 3, 5, 3'-triiodothyronine (T3), a powerful regulator of cell …

Due to the high prostate cancer incidence worldwide, the development of different methods
of treatment continues to be a hot research topic. Since its first clinical application at the …

Background and purpose Despite that incorporating antiangiogenic in combination with
immune-checkpoint inhibitors as the standard first-line treatment for advanced clear cell …

In order to identify new targets and treatment modalities for clear cell renal carcinoma, we
surveyed the literature with respect to microRNAs involved in this disease. In this review, we …