Over the past 40 years, public health measures such as universal newborn screening,
penicillin prophylaxis, vaccinations, and hydroxyurea therapy have led to an impressive …

Sickle cell disease (SCD) predominates in sub‐Saharan Africa, East Mediterranean areas,
Middle East, and India. Nigeria, being the most populous black nation in the world, bears its …

Background Many children with sickle cell disease living in sub-Saharan Africa die before
reaching age 5 years. We estimate the child mortality associated with sickle cell anaemia …

This work aimed to characterize mortality by sickle cell disease in Brazil. The MEDLINE
electronic database was searched using the terms 'mortality'and 'sickle cell disease'and …

Acute chest syndrome is a frequent cause of acute lung disease in children with sickle-cell
disease. Asthma is common in children with sickle-cell disease and is associated with …

Chronic end‐organ complications result in morbidity and mortality in adults with sickle cell
disease (SCD). In a retrospective‐prospective cohort of 150 adults with SCD who received …

Hematopoietic stem cell transplantation (HSCT) is a well-established curative therapy for
patients with sickle cell disease (SCD) when using a human leukocyte antigen (HLA) …

Objective To assess the clinical and laboratory predictors of venous thromboembolism (VTE)
in patients with sickle cell anaemia (SCA) and its relationship to morbidity and mortality …

Introduction: Sickle cell disease (SCD) is an inherited blood disorder characterized by
clinical heterogeneity that may be influenced by environmental factors, ethnicity, race, social …

Background Worldwide, about 20–25 million people are affected by sickle cell disease
(SCD), with 60% of patients living in sub-Saharan Africa. Despite recent therapeutic …