Irreversible electroporation is a new technique to kill cells in targeted tissue, such as tumors,
through a nonthermal mechanism using electric pulses to irrecoverably disrupt the cell …

Thirty years after the publication of the first report on gene electrotransfer in cultured cells by
the delivery of delivering electric pulses, this technology is starting to be applied to humans …

Background For electroporation-based therapies, accurate modeling of the electric field
distribution within the target tissue is important for predicting the treatment volume. In …

Irreversible electroporation (IRE) is emerging as a powerful tool for tumor ablation that
utilizes pulsed electric fields to destabilize the plasma membrane of cancer cells past the …

Aims Pulsed field ablation (PFA) is a non-thermal ablative approach in which cardiomyocyte
death is obtained through irreversible electroporation (IRE). Data correlating the biophysical …

Irreversible electroporation (IRE) ablation uses brief electric pulses to kill a volume of tissue
without damaging the structures contraindicated for surgical resection or thermal ablation …

Several focal therapies are being investigated clinically to treat tumors in which surgery is
contraindicated. Many of these ablation techniques, such as radiofrequency ablation and …

Objective: The use of high-voltage, high-frequency bipolar pulses (HFBPs) is an emerging
electroporation-based therapy for the treatment of solid tumors. In this study, we quantify the …

We introduce and characterize the use of MRI for studying nonthermal irreversible
electroporation (NTIRE) in a vegetative tissue model. NTIRE is a new minimally invasive …

Significance: Irreversible electroporation (IRE) is gaining popularity as a focal ablation
modality for the treatment of unresectable tumors. One clinical limitation of IRE is the …