Quantification of liver fat content with CT and MRI: state of the art

J Starekova, D Hernando, PJ Pickhardt, SB Reeder - Radiology, 2021 - pubs.rsna.org
Hepatic steatosis is defined as pathologically elevated liver fat content and has many
underlying causes. Nonalcoholic fatty liver disease (NAFLD) is the most common chronic …

Liver fat imaging—a clinical overview of ultrasound, CT, and MR imaging

YN Zhang, KJ Fowler, G Hamilton, JY Cui… - The British journal of …, 2018 - academic.oup.com
Hepatic steatosis is a frequently encountered imaging finding that may indicate chronic liver
disease, the most common of which is non-alcoholic fatty liver disease. Non-alcoholic fatty …

Update on multienergy CT: physics, principles, and applications

P Rajiah, A Parakh, F Kay, D Baruah… - Radiographics, 2020 - pubs.rsna.org
Multienergy CT involves acquisition of two or more CT measurements with distinct energy
spectra. Using the differential attenuation of tissues and materials at different x-ray energies …

Accuracy of liver fat quantification with advanced CT, MRI, and ultrasound techniques: prospective comparison with MR spectroscopy

H Kramer, PJ Pickhardt, MA Kliewer… - American journal of …, 2017 - Am Roentgen Ray Soc
OBJECTIVE. The purpose of this study was to prospectively evaluate the accuracy of proton-
density fat-fraction, single-and dual-energy CT (SECT and DECT), gray-scale ultrasound …

Opportunities for new CT contrast agents to maximize the diagnostic potential of emerging spectral CT technologies

BM Yeh, PF FitzGerald, PM Edic, JW Lambert… - Advanced drug delivery …, 2017 - Elsevier
The introduction of spectral CT imaging in the form of fast clinical dual-energy CT enabled
contrast material to be differentiated from other radiodense materials, improved lesion …

Diagnostic modalities of non-alcoholic fatty liver disease: from biochemical biomarkers to multi-omics non-invasive approaches

E Martinou, M Pericleous, I Stefanova, V Kaur… - Diagnostics, 2022 - mdpi.com
Non-Alcoholic Fatty Liver Disease (NAFLD) is currently the most common cause of chronic
liver disease worldwide, and its prevalence is increasing globally. NAFLD is a multifaceted …

Non-invasive imaging methods to evaluate non-alcoholic fatty liver disease with fat quantification: a review

W Jang, JS Song - Diagnostics, 2023 - mdpi.com
Hepatic steatosis without specific causes (eg, viral infection, alcohol abuse, etc.) is called
non-alcoholic fatty liver disease (NAFLD), which ranges from non-alcoholic fatty liver (NAFL) …

Specificity of unenhanced CT for non-invasive diagnosis of hepatic steatosis: implications for the investigation of the natural history of incidental steatosis

PJ Pickhardt, SH Park, L Hahn, SG Lee, KT Bae… - European …, 2012 - Springer
Objectives To determine a highly specific liver attenuation threshold at unenhanced CT for
biopsy-proven moderate to severe hepatic steatosis (≥ 30% at histology). Methods 315 …

Metal artifact reduction by dual-energy computed tomography using energetic extrapolation: a systematically optimized protocol

FG Meinel, B Bischoff, Q Zhang, F Bamberg… - Investigative …, 2012 - journals.lww.com
Objectives Energetic extrapolation is a promising strategy to reduce metal artifacts in dual-
source computed tomography (DSCT). We performed this study to systematically optimize …

Pancreatic steatosis demonstrated at MR imaging in the general population: clinical relevance

JP Kühn, F Berthold, J Mayerle, H Völzke, SB Reeder… - Radiology, 2015 - pubs.rsna.org
Purpose To determine the relationship between pancreatic fat content and type 2 diabetes
and prediabetes. Materials and Methods From the prospective population-based Study of …