Tobacco (Nicotiana tabacum L.) is a widely cultivated crop of the genus Nicotiana. Due to
the highly addictive nature of tobacco products, tobacco smoking remains the leading cause …

Alkaloids represent an extensive group of nitrogen-containing secondary metabolites that
are widely distributed throughout the plant kingdom. The pyridine alkaloids of tobacco …

Secondary metabolites synthesized by the Solanaceous plants are of major therapeutic and
pharmaceutical importance, many of which are commonly obtained from the roots of these …

In tobacco (Nicotiana tabacum), nicotine is the predominant alkaloid. It is produced in the
roots and accumulated mainly in the leaves. Jasmonates play a central signaling role in …

Hairy roots, a plant disease caused by Agrobacterium rhizogenes, show distinctive features
such as high growth rate, unlimited branching, and biochemical and genetic stability. Hairy …

Plants display an amazing ability to synthesize a vast array of secondary metabolites that
are an inexhaustible source of phytochemicals, bioactive molecules some of which impact …

Comfrey (Symphytum officinale) is a medicinal plant with anti-inflammatory, analgesic, and
proliferative properties. However, its pharmaceutical application is hampered by the co …

Nicotine biosynthesis in tobacco (Nicotiana tabacum L.) is highly regulated by jasmonic acid
(JA). Two nuclear loci, A and B (renamed NIC1 and NIC2) have been identified that mediate …

Alkaloids are important compounds found in Nicotiana plants, essential in plant defense
against herbivores. The main alkaloid of Nicotiana tabacum, nicotine, is produced in roots …

Motivation exists to develop tobacco cultivars with reduced nicotine content for the purpose
of facilitating compliance with expected tobacco product regulations that could mandate the …