Direct observation of adaptive tracking on ecological time scales in Drosophila

SM Rudman, SI Greenblum, S Rajpurohit… - Science, 2022 - science.org
Direct observation of evolution in response to natural environmental change can resolve
fundamental questions about adaptation, including its pace, temporal dynamics, and …

Microbiome composition shapes rapid genomic adaptation of Drosophila melanogaster

SM Rudman, S Greenblum… - Proceedings of the …, 2019 - National Acad Sciences
Population genomic data has revealed patterns of genetic variation associated with
adaptation in many taxa. Yet understanding the adaptive process that drives such patterns is …

Estimating the genome-wide contribution of selection to temporal allele frequency change

V Buffalo, G Coop - … of the National Academy of Sciences, 2020 - National Acad Sciences
Rapid phenotypic adaptation is often observed in natural populations and selection
experiments. However, detecting the genome-wide impact of this selection is difficult since …

Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA …

M Kapun, MG Barrón, F Staubach… - Molecular Biology …, 2020 - academic.oup.com
Genetic variation is the fuel of evolution, with standing genetic variation especially important
for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of …

The adaptive significance of chromosomal inversion polymorphisms in Drosophila melanogaster

M Kapun, T Flatt - Molecular ecology, 2019 - Wiley Online Library
Chromosomal inversions, structural mutations that reverse a segment of a chromosome,
cause suppression of recombination in the heterozygous state. Several studies have shown …

Drosophila Evolution over Space and Time (DEST): A New Population Genomics Resource

M Kapun, JCB Nunez… - Molecular biology …, 2021 - academic.oup.com
Drosophila melanogaster is a leading model in population genetics and genomics, and a
growing number of whole-genome data sets from natural populations of this species have …

A Population Genomic Assessment of Three Decades of Evolution in a Natural Drosophila Population

JD Lange, H Bastide, JB Lack… - Molecular Biology and …, 2022 - academic.oup.com
Population genetics seeks to illuminate the forces shaping genetic variation, often based on
a single snapshot of genomic variation. However, utilizing multiple sampling times to study …

Fluctuating environments maintain genetic diversity through neutral fitness effects and balancing selection

F Abdul-Rahman, D Tranchina… - Molecular Biology and …, 2021 - academic.oup.com
Genetic variation is the raw material upon which selection acts. The majority of
environmental conditions change over time and therefore may result in variable selective …

[PDF][PDF] Population Genomics on the Fly: Recent Advances in Drosophila

A Haudry, S Laurent, M Kapun - Statistical population genomics, 2020 - library.oapen.org
Drosophila melanogaster, a small dipteran of African origin, represents one of the best-
studied model organisms. Early work in this system has uniquely shed light on the basic …

The genomic scale of fluctuating selection in a natural plant population

JK Kelly - Evolution letters, 2022 - academic.oup.com
This study characterizes evolution at≈ 1.86 million Single Nucleotide Polymorphisms
(SNPs) within a natural population of yellow monkeyflower (Mimulus guttatus). Most SNPs …