Current advances in chitosan nanoparticles based oral drug delivery for colorectal cancer treatment

H Choukaife, S Seyam, B Alallam… - International journal …, 2022 - Taylor & Francis
As per the WHO, colorectal cancer (CRC) caused around 935,173 deaths worldwide in 2020
in both sexes and at all ages. The available anticancer therapies including chemotherapy …

[HTML][HTML] Biomaterials-enhanced intranasal delivery of drugs as a direct route for brain targeting

E Marcello, V Chiono - International Journal of Molecular Sciences, 2023 - mdpi.com
Intranasal (IN) drug delivery is a non-invasive and effective route for the administration of
drugs to the brain at pharmacologically relevant concentrations, bypassing the blood–brain …

Native PLGA nanoparticles regulate APP metabolism and protect neurons against β-amyloid toxicity: Potential significance in Alzheimer's disease pathology

Q Wu, G Karthivashan, M Nakhaei-Nejad… - International Journal of …, 2022 - Elsevier
Biodegradable poly (lactic-co-glycolic acid)(PLGA) nanoparticles have been used
extensively in delivering drugs to target tissues due to their excellent biocompatibility …

[HTML][HTML] PLGA-based nanoplatforms in drug delivery for inhibition and destruction of microbial biofilm

A Shariati, Z Chegini, E Ghaznavi-Rad… - Frontiers in Cellular …, 2022 - frontiersin.org
The biofilm community of microorganisms has been identified as the dominant mode of
microbial growth in nature and a common characteristic of different microorganisms such as …

[HTML][HTML] The recent applications of plga-based nanostructures for ischemic stroke

J Yan, L Huang, J Feng, X Yang - Pharmaceutics, 2023 - mdpi.com
With the accelerated development of nanotechnology in recent years, nanomaterials have
become increasingly prevalent in the medical field. The poly (lactic acid–glycolic acid) …

[HTML][HTML] Nanoparticle based periodontal drug delivery–A review on current trends and future perspectives

AM Basudan - The Saudi dental journal, 2022 - Elsevier
Introduction Periodontitis is a chronic inflammatory disease, resulting due to host immune
response against subgingival biofilm. Most conventional treatment protocols aim to control …

[HTML][HTML] Rosmarinic acid-loaded polymeric nanoparticles prepared by low-energy nano-emulsion templating: Formulation, biophysical characterization, and in vitro …

J García-Melero, JJ López-Mitjavila, MJ García-Celma… - Materials, 2022 - mdpi.com
Rosmarinic acid (RA), a caffeic acid derivative, has been loaded in polymeric nanoparticles
made up of poly (lactic-co-glycolic acid)(PLGA) through a nano-emulsion templating process …

A review on PLGA particles as a sustained drug-delivery system and its effect on the retina

S Marquina, M Ozgul, K Robertson-Brown… - Experimental Eye …, 2023 - Elsevier
In this review, the designs and recent developments of polymer-based drug delivery of Poly
(lactic-co-glycolic acid)(PLGA) will be discussed for the possible treatment of age-related …

Molybdenum-iodine cluster loaded polymeric nanoparticles allowing a coupled therapeutic action with low side toxicity for treatment of ovarian cancer

A Verger, G Dollo, S Martinais, Y Molard… - Journal of …, 2022 - Elsevier
The ability of cancer cells to develop resistance to anti-cancer drugs, known as multidrug
resistance, remains a major cause of tumor recurrence and cancer metastasis. This work …

Microstructure Formation and Characterization of Long-Acting Injectable Microspheres: The Gateway to Fully Controlled Drug Release Pattern

M Wang, S Wang, C Zhang, M Ma, B Yan… - International Journal …, 2024 - Taylor & Francis
Long-acting injectable microspheres have been on the market for more than three decades,
but if calculated on the brand name, only 12 products have been approved by the FDA due …