Candida and Candidiasis—Opportunism Versus Pathogenicity: A Review of the Virulence Traits

CN Ciurea, IB Kosovski, AD Mare, F Toma… - Microorganisms, 2020 - mdpi.com
One of the most important questions in microbiology nowadays, is how apparently harmless,
commensal yeasts like Candida spp. can cause a rising number of infections. The …

[HTML][HTML] Genome plasticity in Candida albicans: A cutting-edge strategy for evolution, adaptation, and survival

IE Mba, EI Nweze, EA Eze… - Infection, Genetics and …, 2022 - Elsevier
Candida albicans is the most implicated fungal species that grows as a commensal or
opportunistic pathogen in the human host. It is associated with many life-threatening …

Two-speed genome evolution drives pathogenicity in fungal pathogens of animals

T Wacker, N Helmstetter, D Wilson… - Proceedings of the …, 2023 - National Acad Sciences
The origins and evolution of virulence in amphibian-infecting chytrids Batrachochytrium
dendrobatidis (Bd) and Batrachochytrium salamandrivorans (Bsal) are largely unknown …

Genome-wide analysis of heat stress-stimulated transposon mobility in the human fungal pathogen Cryptococcus deneoformans

A Gusa, V Yadav, C Roth, JD Williams… - Proceedings of the …, 2023 - National Acad Sciences
We recently reported transposon mutagenesis as a significant driver of spontaneous
mutations in the human fungal pathogen Cryptococcus deneoformans during murine …

Mitotic recombination between homologous chromosomes drives genomic diversity in diatoms

P Bulankova, M Sekulić, D Jallet, C Nef… - Current Biology, 2021 - cell.com
Diatoms, an evolutionarily successful group of microalgae, display high levels of
intraspecific genetic variability in natural populations. However, the contribution of various …

Systemic alterations of cancer cells and their boost by polyploidization: unicellular attractor (UCA) model

AE Vinogradov, OV Anatskaya - International Journal of Molecular …, 2023 - mdpi.com
Using meta-analyses, we introduce a unicellular attractor (UCA) model integrating essential
features of the 'atavistic reversal','cancer attractor','somatic mutation','genome chaos', and …

The structural, functional and evolutionary impact of transposable elements in eukaryotes

D Almojil, Y Bourgeois, M Falis, I Hariyani, J Wilcox… - Genes, 2021 - mdpi.com
Transposable elements (TEs) are nearly ubiquitous in eukaryotes. The increase in genomic
data, as well as progress in genome annotation and molecular biology techniques, have …

Transposon mobilization in the human fungal pathogen Cryptococcus is mutagenic during infection and promotes drug resistance in vitro

A Gusa, JD Williams, JE Cho… - Proceedings of the …, 2020 - National Acad Sciences
When transitioning from the environment, pathogenic microorganisms must adapt rapidly to
survive in hostile host conditions. This is especially true for environmental fungi that cause …

Evolutionary and genomic comparisons of hybrid uninucleate and nonhybrid Rhizoctonia fungi

C Li, Z Guo, S Zhou, Q Han, M Zhang, Y Peng… - Communications …, 2021 - nature.com
The basidiomycetous fungal genus, Rhizoctonia, can cause severe damage to many plants
and is composed of multinucleate, binucleate, and uninucleate species differing in …

Parasexuality of Candida Species

A Mishra, A Forche, MZ Anderson - Frontiers in Cellular and Infection …, 2021 - frontiersin.org
While most fungi have the ability to reproduce sexually, multiple independent lineages have
lost meiosis and developed parasexual cycles in its place. Emergence of parasexual cycles …