Sažetak The complex process of biological aging, as an intrinsic feature of living beings, is
the result of genetic and, to a greater extent, environmental factors and time. For many of the …

The ageing of the global population brings about unprecedented challenges. Chronic age‐
related diseases in an increasing number of people represent an enormous burden for …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Senile osteoporosis (SOP) is widely regarded as one of the typical aging-related diseases
due to a decrease in bone mass and the destruction in microarchitecture. The inhibition of …

Mass cytometry (cytometry by time-of-flight detection [CyTOF]) is a bioanalytical technique
that enables the identification and quantification of diverse features of cellular systems with …

Proximity labeling has emerged as a powerful strategy for interrogating cell-cell interactions.
However, the nanometer-scale labeling radius impedes the use of current methods for …

The subset of the proteome that contains enzymes in their catalytically active form can be
interrogated by using probes targeted toward individual specific enzymes. A subset of such …

Detection of senescence-associated β-galactosidase (SA-β-gal) activity at an increased
lysosomal pH is one of the most reliable approaches for probing senescent cells. Herein, we …

Mass cytometry is a revolutionary technology that allows for the simultaneous quantification
of> 40 different biomarkers with cellular resolution. The biomarkers are detected using metal …

Tellurophene-bearing small molecules have emerged as valuable tools for localizing
cellular activities in vivo using mass cytometry. To broaden the utility of tellurophenes in …