Aneuploidy has been recognized as a hallmark of tumorigenesis for more than 100 years,
but the connection between chromosomal errors and malignant growth has remained …

Background Common fetal aneuploidies include Down syndrome (trisomy 21 or T21),
Edward syndrome (trisomy 18 or T18), Patau syndrome (trisomy 13 or T13), Turner …

Importance Trisomy 13 and 18 are genetic diagnoses with characteristic physical features,
organ anomalies, and neurodevelopmental disability. Most children with these disorders die …

The aim of the study is to determine the prevalence, outcomes, and survival (among live
births [LB]), in pregnancies diagnosed with trisomy 13 (T13) and 18 (T18), by congenital …

Trisomy 13 (T13) and trisomy 18 (T18) are among the most prevalent autosomal trisomies.
Both are associated with a very high risk of mortality. Numerous instances, however, of long …

The aim of this study was to examine the prevalence of trisomies 18 and 13 in Europe and
the prevalence of associated anomalies. Twenty‐five population‐based registries in 16 …

Trisomy 13 and 18 are life‐limiting conditions for which a palliative approach is frequently
recommended. The objective of this study was to examine parental goals/decisions, the …

METHODS: Data from the 2004 to 2015 Pediatric Health Information System database were
used to identify inpatients with T13 or T18 and CHD. Data were restricted to newborns with …

Background The purpose of this study is to report short-and long-term outcomes after
congenital heart defect (CHD) interventions in patients with trisomy 13 or 18. Methods A …

Chromosomal instability (CIN) and aneuploidy are similar concepts but not synonymous.
CIN is the process that leads to chromosome copy number alterations, and aneuploidy is the …