The role of early growth response 1 (EGR1) in brain plasticity and neuropsychiatric disorders

F Duclot, M Kabbaj - Frontiers in behavioral neuroscience, 2017 - frontiersin.org
It is now clearly established that complex interactions between genes and environment are
involved in multiple aspects of neuropsychiatric disorders, from determining an individual's …

The many faces of solitary fibrous tumor; diversity of histological features, differential diagnosis and role of molecular studies and surrogate markers in avoiding …

MU Tariq, NU Din, J Abdul-Ghafar, YK Park - Diagnostic Pathology, 2021 - Springer
Abstract Background Solitary Fibrous Tumor (SFT) is a distinct soft tissue neoplasm
associated with NAB2-STAT6 gene fusion. It can involve a number of anatomic sites and …

Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing

DR Robinson, YM Wu, S Kalyana-Sundaram, X Cao… - Nature …, 2013 - nature.com
A 44-year old woman with recurrent solitary fibrous tumor (SFT)/hemangiopericytoma was
enrolled in a clinical sequencing program including whole-exome and transcriptome …

Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein

L Schweizer, C Koelsche, F Sahm, RM Piro… - Acta …, 2013 - Springer
Non-central nervous system hemangiopericytoma (HPC) and solitary fibrous tumor (SFT)
are considered by pathologists as two variants of a single tumor entity now subsumed under …

Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins

T Herdegen, JD Leah - Brain research reviews, 1998 - Elsevier
This article reviews findings up to the end of 1997 about the inducible transcription factors
(ITFs) c-Jun, JunB, JunD, c-Fos, FosB, Fra-1, Fra-2, Krox-20 (Egr-2) and Krox-24 (NGFI-A …

Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors

J Chmielecki, AM Crago, M Rosenberg, R O'Connor… - Nature …, 2013 - nature.com
Solitary fibrous tumors (SFTs) are rare mesenchymal tumors. Here, we describe the
identification of a NAB2-STAT6 fusion from whole-exome sequencing of 17 SFTs. Analysis …

[HTML][HTML] Multilineage transcriptional priming and determination of alternate hematopoietic cell fates

P Laslo, CJ Spooner, A Warmflash, DW Lancki, HJ Lee… - Cell, 2006 - cell.com
Hematopoietic stem cells and their progenitors exhibit multilineage patterns of gene
expression. Molecular mechanisms underlying the generation and refinement of these …

Localization of apical epithelial determinants by the basolateral PDZ protein Scribble

D Bilder, N Perrimon - Nature, 2000 - nature.com
The generation of membrane domains with distinct protein constituents is a hallmark of cell
polarization. In epithelia, segregation of membrane proteins into apical and basolateral …

[HTML][HTML] Regulation of MAPKs by growth factors and receptor tyrosine kinases

M Katz, I Amit, Y Yarden - Biochimica et Biophysica Acta (BBA)-Molecular …, 2007 - Elsevier
Multiple growth-and differentiation-inducing polypeptide factors bind to and activate
transmembrane receptors tyrosine kinases (RTKs), to instigate a plethora of biochemical …

Regulation of life and death by the zinc finger transcription factor Egr‐1

G Thiel, G Cibelli - Journal of cellular physiology, 2002 - Wiley Online Library
The biosynthesis of the zinc finger transcription factor Egr‐1 is stimulated by many
extracellular signaling molecules including hormones, neurotransmitters, growth and …