The gastrointestinal tract has the important task of absorbing nutrients, a complex process
that requires an intact barrier allowing the passage of nutrients but that simultaneously …

Carbon monoxide (CO) is attracting increasing attention because of its role as a
gasotransmitter with cytoprotective and homeostatic properties. Carbon monoxide releasing …

Carbon monoxide (CO) is increasingly being accepted as a cytoprotective and homeostatic
molecule with important signalling capabilities in physiological and pathophysiological …

The use of Carbon Monoxide (CO) as a therapeutic agent has already been tested in human
clinical trials. Pre-clinically, CO gas administration proved beneficial in animal models of …

Carbon monoxide (CO) is continuously produced in mammalian cells during the
degradation of heme. It is a stable gaseous molecule that reacts selectively with transition …

Heme oxygenases are composed of two isozymes, Hmox1 and Hmox2, that catalyze the
degradation of heme to carbon monoxide (CO), ferrous iron, and biliverdin, the latter of …

Postoperative ileus (POI) is a common clinical condition arising after almost every
abdominal surgical procedure, leading to increased patient morbidity and prolonged …

Significance: Heme oxygenase enzymes, which exist as constitutive (HO-2) and inducible
(HO-1) isoforms, degrade heme to carbon monoxide (CO) and the bile pigment biliverdin. In …

Postoperative ileus (POI) is an abnormal pattern of gastrointestinal motility characterized by
nausea, vomiting, abdominal distension and/or delayed passage of flatus or stool, which …

Postoperative ileus, which develops after each abdominal surgical procedure, is an
iatrogenic disorder characterized by a transient inhibition of gastrointestinal motility. Its …