Diagnosis and treatment of Kaposi sarcoma

JW Schneider, DP Dittmer - American journal of clinical dermatology, 2017 - Springer
Kaposi sarcoma (KS) is the most common neoplasm of people living with HIV today. In Sub-
Saharan Africa, KS is among the most common cancers in men, overall. Not only HIV …

Update on KSHV epidemiology, Kaposi Sarcoma pathogenesis, and treatment of Kaposi Sarcoma

TS Uldrick, D Whitby - Cancer letters, 2011 - Elsevier
Much has been learned since the discovery of KSHV in 1994 about its epidemiology and
pathology but much of what has been learned has yet to be translated into clinical practice …

Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome clone

KF Brulois, H Chang, ASY Lee, A Ensser… - Journal of …, 2012 - Am Soc Microbiol
Efficient genetic modification of herpesviruses such as Kaposi's sarcoma-associated
herpesvirus (KSHV) has come to rely on bacterial artificial chromosome (BAC) technology …

KSHV: pathways to tumorigenesis and persistent infection

L Giffin, B Damania - Advances in virus research, 2014 - Elsevier
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8) is
the etiologic agent of Kaposi's sarcoma, primary effusion lymphoma, and multicentric …

Pomalidomide for symptomatic Kaposi's sarcoma in people with and without HIV infection: a phase I/II study

MN Polizzotto, TS Uldrick, KM Wyvill… - Journal of Clinical …, 2016 - ascopubs.org
Purpose Kaposi's sarcoma (KS) is a multicentric tumor caused by Kaposi's sarcoma–
associated herpesvirus. Unmet needs include therapies that are oral, anthracycline sparing …

A randomized controlled trial of highly active antiretroviral therapy versus highly active antiretroviral therapy and chemotherapy in therapy-naive patients with HIV …

A Mosam, F Shaik, TS Uldrick… - JAIDS Journal of …, 2012 - journals.lww.com
Background: The optimal approach to HIV-associated Kaposi sarcoma (HIV-KS) in sub-
Saharan Africa is unknown. With large-scale rollout of highly active antiretroviral therapy …

Immune reconstitution inflammatory syndrome associated with Kaposi sarcoma: higher incidence and mortality in Africa than in the UK

E Letang, JJ Lewis, M Bower, A Mosam, M Borok… - Aids, 2013 - journals.lww.com
Objectives: To assess the incidence, predictors, and outcomes of Kaposi sarcoma-
associated paradoxical immune reconstitution inflammatory syndrome (KS-IRIS) in …

Kaposi sarcoma: review and medical management update

M Fatahzadeh - Oral surgery, oral medicine, oral pathology and oral …, 2012 - Elsevier
Despite recent advances in our understanding of pathogenic mechanisms involved, the true
nature of Kaposi sarcoma remains an enigma. Four clinical variants have been described for …

Molecular and cellular mechanisms of KSHV oncogenesis of Kaposi's sarcoma associated with HIV/AIDS

LE Cavallin, P Goldschmidt-Clermont… - PLoS pathogens, 2014 - journals.plos.org
Twenty years after its discovery [1], Kaposi's sarcoma herpesvirus (KSHV) or human
herpesvirus-8 (HHV-8) continues to be an enigmatic oncovirus, while AIDS-associated …

Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults

OF Gbabe, CI Okwundu, M Dedicoat… - Cochrane Database …, 2014 - cochranelibrary.com
Background Kaposi's sarcoma remains the most common cancer in Sub‐Saharan Africa and
the second most common cancer in HIV‐infected patients worldwide. Since the introduction …