Highlights•IMS improves analytical performance of MS imaging of biological tissue
samples.•Improvements in specificity and imaging accuracy are achieved for small …

There are only 30,000 human genes, which, according to the central dogma from biology, it
means that there should be 30,000 mRNA and 30,000 proteins. However, there are at least …

The secretome includes all macromolecules secreted by cells, in particular conditions at
defined times, allowing cell–cell communication. Cancer cell secretomes that are altered …

Detection of breast cancer (BC) in young women is challenging because mammography, the
most common tool for detecting BC, is not effective on the dense breast tissue characteristic …

The etiology and pathogenesis of many psychiatric disorders are unclear with many
signaling pathways and complex interactions still unknown. Primary information provided …

Breast cancer (BC) remains a major cause of mortality, and early detection is considered
important for reducing BC‐associated deaths. Early detection of BC is challenging in young …

Mass spectrometry (MS) is the core for advanced methods in proteomic experiments. When
effectively used, proteomics may provide extensive information about proteins and their post …

Within the past years, we have witnessed a great improvement is mass spectrometry (MS)
and proteomics approaches in terms of instrumentation, protein fractionation, and …

Within the past years, we have witnessed a great improvement in mass spectrometry (MS)
and proteomics approaches in terms of instrumentation, protein fractionation, and …

Although mammography and treatment advances have led to declines in breast cancer
mortality in the United States, breast cancer remains a major cause of morbidity and …