Advances in ferritin physiology and possible implications in bacterial infection

CM Gehrer, AM Mitterstiller, P Grubwieser… - International journal of …, 2023 - mdpi.com
Due to its advantageous redox properties, iron plays an important role in the metabolism of
nearly all life. However, these properties are not only a boon but also the bane of such life …

[HTML][HTML] Molecular clusters in confined spaces

A Braschinsky, JW Steed - Coordination Chemistry Reviews, 2022 - Elsevier
Confinement chemistry is a growing field with many potential applications in the synthetic,
catalytic and especially pharmaceutical industries. Confinement of materials can reveal …

Directing polymorph specific calcium carbonate formation with de novo protein templates

FA Davila-Hernandez, B Jin, H Pyles, S Zhang… - Nature …, 2023 - nature.com
Biomolecules modulate inorganic crystallization to generate hierarchically structured
biominerals, but the atomic structure of the organic-inorganic interfaces that regulate …

Ferritin nanocomposites for the selective delivery of photosensitizing ruthenium-polypyridyl compounds to cancer cells

L Conti, S Ciambellotti, GE Giacomazzo… - Inorganic Chemistry …, 2022 - pubs.rsc.org
Herein, we report on the successful encapsulation into human H-ferritin of two highly
charged Ru (II) polypyridyl complexes,[Ru (phen) 2L′] 2+(Ru1, with L′= 4, 4′-(2, 5, 8, 11 …

[HTML][HTML] 19F: A small probe for a giant protein

L Cosottini, S Zineddu, L Massai, V Ghini… - Journal of Inorganic …, 2023 - Elsevier
Herein we describe a method for the efficient production (∼ 90% fluorination) of 5-F-Trp
human H ferritin via the selective incorporation of 19 F into the side chain of W93 using 5 …

Biochemical Characterization of Caenorhabditis elegans Ferritins

SSM Mubarak, TR Malcolm, HG Brown, E Hanssen… - Biochemistry, 2023 - ACS Publications
The nematode Caenorhabditis elegans contains genes for two types of ferritin (ftn-1 and ftn-
2) that express FTN-1 and FTN-2. We have expressed and purified both proteins and …

Growth Process of Fe–O Nanoclusters with Different Sizes Biosynthesized by Protein Nanocages

W Wang, H Xi, D Fu, D Ma, W Gong… - Journal of the …, 2024 - ACS Publications
All protein-directed syntheses of metal nanoclusters (NCs) and nanoparticles (NPs) have
attracted considerable attention because protein scaffolds provide a unique metal …

Folding of an intrinsically disordered iron-binding peptide in response to sedimentation revealed by cryo-EM

G Davidov, G Abelya, R Zalk, B Izbicki… - Journal of the …, 2020 - ACS Publications
Biomineralization is mediated by specialized proteins that guide and control mineral
sedimentation. In many cases, the active regions of these biomineralization proteins are …

Observation of the protein-inorganic interface of ferritin by cryo-electron microscopy

S Sen, A Thaker, A Haymaker, D Williams… - Journal of the …, 2024 - ACS Publications
Visualizing the structure of the protein-inorganic interface is critically important for a more
complete understanding of biomineralization. Unfortunately, there are limited approaches for …

Bacterioferritin nanocage structures uncover the biomineralization process in ferritins

C Jobichen, T Ying Chong, R Rattinam, S Basak… - PNAS …, 2023 - academic.oup.com
Iron is an essential element involved in various metabolic processes. The ferritin family of
proteins forms nanocage assembly and is involved in iron oxidation, storage, and …