The c statistic, or area under the receiver operating characteristic (ROC) curve, achieved
popularity in diagnostic testing, in which the test characteristics of sensitivity and specificity …

Background: Studies of diagnostic accuracy are subject to different sources of bias and
variation than studies that evaluate the effectiveness of an intervention. Little is known about …

Background—Atrial fibrillation (AF) and heart failure (HF) frequently coexist and together
confer an adverse prognosis. The association of AF with HF subtypes has not been well …

Background—Heart failure (HF) is a prevalent and deadly disease, and preventive
strategies focused on at-risk individuals are needed. Current HF prediction models have not …

Objectives. This study was designed to determine the most appropriate method to normalize
left ventricular mass for body size. Background. Left ventricular mass has been normalized …

Grading quality of evidence and strength of recommendations for diagnostic tests and strategies
| The BMJ Skip to main content Intended for healthcare professionals Access provided by …

Background Mitral-valve prolapse has been described as a common disease with frequent
complications. To determine the prevalence of mitral-valve prolapse in the general …

Objective: The purpose of this study was to evaluate the relationship of left ventricular (LV)
mass and geometry measured with cardiac magnetic resonance imaging (MRI) to incident …

Objectives. This study examined the relations of echocardiographically determined left
ventricular (LV) mass and hypertrophy to the risk of sudden death. Background …

Objective.—To determine the relationship of varying degrees of obesity with left ventricular
mass and geometry. Design.—Survey. Setting.—Population-based epidemiologic study …