5‐HT radioligands for human brain imaging with PET and SPECT

LM Paterson, BR Kornum, DJ Nutt… - Medicinal research …, 2013 - Wiley Online Library
The serotonergic system plays a key modulatory role in the brain and is the target for many
drug treatments for brain disorders either through reuptake blockade or via interactions at …

Quetiapine: preclinical studies, pharmacokinetics, drug interactions, and dosing

CB Nemeroff, B Kinkead, J Goldstein - Journal of Clinical …, 2002 - psychiatrist.com
Quetiapine is a novel dibenzothiazepine atypical antipsychotic. Quetiapine shows affinity for
various neurotransmitter receptors including serotonin, dopamine, histamine, and …

A double-blind, randomized, placebo-controlled study of quetiapine as adjunctive treatment for adolescent mania

MP Delbello, ML Schwiers, HL Rosenberg… - Journal of the American …, 2002 - Elsevier
OBJECTIVE:: This randomized, double-blind, placebo-controlled study examined the
efficacy and tolerability of quetiapine in combination with divalproex (DVP) for acute mania …

Cortical Serotonin 5-HT 2A Receptor Binding and Social Communication in Adults With Asperger's Syndrome: An in Vivo SPECT Study

DGM Murphy, E Daly, N Schmitz… - American Journal of …, 2006 - Am Psychiatric Assoc
Objective: The cause of autistic spectrum disorder (ie, autism and Asperger's syndrome) is
unknown. The serotonergic (5-HT) system may be especially implicated. However, cortical 5 …

Hallucinations in schizophrenia, sensory impairment, and brain disease: a unifying model

RP Behrendt, C Young - Behavioral and Brain sciences, 2004 - cambridge.org
Based on recent insight into the thalamocortical system and its role in perception and
conscious experience, a unified pathophysiological framework for hallucinations in …

Psilocybin for Depression: From Credibility to Feasibility, What's Missing?

A Munafò, D Arillotta, G Mannaioni, F Schifano… - Pharmaceuticals, 2022 - mdpi.com
Psilocybin has been suggested as a promising transdiagnostic treatment strategy for a wide
range of psychiatric disorders. Recent findings showed that psychedelic-assisted/” …

Dopamine and antipsychotic drug action revisited

HM Jones, LS Pilowsky - The British Journal of Psychiatry, 2002 - cambridge.org
JONES & PILOWSKY in the main, in the main, unhelpful in the treatment of unhelpful in the
treatment of poorly responsive schizophrenia (Thompson, 1994). Finally, clozapine, a …

Quetiapine augmentation of treatment-resistant depression: a comparison with lithium

JP Dorée, JD Rosiers, V Lew, A Gendron… - … medical research and …, 2007 - Taylor & Francis
Objective: The prevalence of and morbidity associated with treatment-resistant depression
has motivated the exploration of treatment alternatives. In this study, quetiapine was …

Effects of the antipsychotic quetiapine on sleep and breathing: a review of clinical findings and potential mechanisms

C Fauska, T Bastiampillai, RJ Adams… - Journal of Sleep …, 2024 - Wiley Online Library
Quetiapine is an antipsychotic medication indicated for schizophrenia and bipolar disorder.
However, quetiapine also has hypnotic properties and as such is increasingly being …

[HTML][HTML] Different patterns of 5-HT receptor and transporter dysfunction in neuropsychiatric disorders–a comparative analysis of in vivo imaging findings

S Nikolaus, HW Müller, H Hautzel - Reviews in the Neurosciences, 2016 - degruyter.com
Impairment of serotonin receptor and transporter function is increasingly recognized to play
a major role in the pathophysiology of neuropsychiatric diseases including anxiety disorder …