Introduction The existing treatment modalities for knee osteoarthritis (OA) do not actually
address the pathology. Biological therapies, including those using material derived from …

Purpose The onset of OA is affected by a variety of factors, which eventually lead to the loss
of cartilage in the joints, the formation of osteophytes, the loss of normal knee mobility, and …

Background The success of stem cell therapy for knee osteoarthritis (KOA) in preclinical
animal models has accelerated the pace of clinical translation. However, it remains …

Producing tremendous amounts of stress and financial burden on the global patient
population and healthcare systems around the world, most current modalities of treatment …

Cartilage degeneration is a key feature of aging and osteoarthritis, characterized by the
progressive deterioration of joint function, pain, and limited mobility. Current treatments …

This study aimed to examine the anti-inflammatory properties of boric acid (BA) in treating
knee osteoarthritis (KOA) in rats, evaluating its biochemical and histopathological …

Osteoarthritis (OA) is the most common type of arthritis that can affect all joint structures. The
primary goals of osteoarthritis treatment are to alleviate pain, reduce functional limitations …

Abstract Background Mesenchymal stromal cells (MSCs) are increasingly employed in
regenerative medicine approaches for their immunomodulatory and anti-inflammatory …

Background Cell and cell-derived therapies sourced from perinatal biologic material have
arisen as the popularity of stem cell treatments grew in the United States. The mythical …

Inflammatory bowel disease (IBD) is characterized by periods of flare-ups and remission. It is
likely to be an autoimmune in origin, presenting persistent therapeutic challenges despite …