Plant electrical signals: A multidisciplinary challenge

JH Li, LF Fan, DJ Zhao, Q Zhou, JP Yao… - Journal of Plant …, 2021 - Elsevier
Plant electrical signals, an early event in the plant–stimulus interaction, rapidly transmit
information generated by the stimulus to other organs, and even the whole plant, to promote …

Seizure onset zone identification from iEEG: A review

SS Balaji, KK Parhi - IEEE Access, 2022 - ieeexplore.ieee.org
This paper discusses the various methods of identifying the seizure onset zone (SOZ) from
the intracranial electroencephalography (iEEG) data. Epilepsy, also known as seizure …

Virtual cortical resection reveals push-pull network control preceding seizure evolution

AN Khambhati, KA Davis, TH Lucas, B Litt, DS Bassett - Neuron, 2016 - cell.com
In∼ 20 million people with drug-resistant epilepsy, focal seizures originating in
dysfunctional brain networks will often evolve and spread to surrounding tissue, disrupting …

Dynamic network drivers of seizure generation, propagation and termination in human neocortical epilepsy

AN Khambhati, KA Davis, BS Oommen… - PLoS computational …, 2015 - journals.plos.org
The epileptic network is characterized by pathologic, seizure-generating 'foci'embedded in a
web of structural and functional connections. Clinically, seizure foci are considered optimal …

Crowdsourcing seizure detection: algorithm development and validation on human implanted device recordings

SN Baldassano, BH Brinkmann, H Ung, T Blevins… - Brain, 2017 - academic.oup.com
There exist significant clinical and basic research needs for accurate, automated seizure
detection algorithms. These algorithms have translational potential in responsive …

Spatial distribution of interictal spikes fluctuates over time and localizes seizure onset

EC Conrad, SB Tomlinson, JN Wong, KF Oechsel… - Brain, 2020 - academic.oup.com
The location of interictal spikes is used to aid surgical planning in patients with medically
refractory epilepsy; however, their spatial and temporal dynamics are poorly understood. In …

Intracranial electroencephalographic biomarker predicts effective responsive neurostimulation for epilepsy prior to treatment

BH Scheid, JM Bernabei, AN Khambhati… - …, 2022 - Wiley Online Library
Objective Despite the overall success of responsive neurostimulation (RNS) therapy for drug‐
resistant focal epilepsy, clinical outcomes in individuals vary significantly and are hard to …

Characterizing the role of the structural connectome in seizure dynamics

P Shah, A Ashourvan, F Mikhail, A Pines, L Kini… - Brain, 2019 - academic.oup.com
How does the human brain's structural scaffold give rise to its intricate functional dynamics?
This is a central question in translational neuroscience that is particularly relevant to …

Time-evolving controllability of effective connectivity networks during seizure progression

BH Scheid, A Ashourvan, J Stiso… - Proceedings of the …, 2021 - National Acad Sciences
Over one third of the estimated 3 million people with epilepsy in the United States are
medication resistant. Responsive neurostimulation from chronically implanted electrodes …

[HTML][HTML] A framework For brain atlases: Lessons from seizure dynamics

AY Revell, AB Silva, TC Arnold, JM Stein, SR Das… - NeuroImage, 2022 - Elsevier
Brain maps, or atlases, are essential tools for studying brain function and organization. The
abundance of available atlases used across the neuroscience literature, however, creates …