The immunomodulatory functions of butyrate

MT Siddiqui, GAM Cresci - Journal of inflammation research, 2021 - Taylor & Francis
The gastrointestinal (GI) system contains many different types of immune cells, making it a
key immune organ system in the human body. In the last decade, our knowledge has …

Evolving role of diet in the pathogenesis and treatment of inflammatory bowel diseases

A Levine, RS Boneh, E Wine - Gut, 2018 - gut.bmj.com
Recent advances in basic and clinical science over the last 3 years have dramatically
altered our appreciation of the role of diet in inflammatory bowel diseases (IBD). The marked …

Parabacteroides distasonis uses dietary inulin to suppress NASH via its metabolite pentadecanoic acid

W Wei, CC Wong, Z Jia, W Liu, C Liu, F Ji, Y Pan… - Nature …, 2023 - nature.com
Non-alcoholic steatohepatitis (NASH) is the severe form of non-alcoholic fatty liver disease,
and is characterized by liver inflammation and fat accumulation. Dietary interventions, such …

Role of short-chain fatty acids in colonic inflammation, carcinogenesis, and mucosal protection and healing

CM van der Beek, CHC Dejong, FJ Troost… - Nutrition …, 2017 - academic.oup.com
Short-chain fatty acids (SCFAs), mainly acetate, propionate, and butyrate, produced by
microbial fermentation of undigested food substances are believed to play a beneficial role …

Effects of dietary components on intestinal permeability in health and disease

K Khoshbin, M Camilleri - American Journal of Physiology …, 2020 - journals.physiology.org
Altered intestinal permeability plays a role in many pathological conditions. Intestinal
permeability is a component of the intestinal barrier. This barrier is a dynamic interface …

Short chain fatty acids in human gut and metabolic health

EE Blaak, EE Canfora, S Theis, G Frost… - Beneficial …, 2020 - wageningenacademic.com
Evidence is accumulating that short chain fatty acids (SCFA) play an important role in the
maintenance of gut and metabolic health. The SCFA acetate, propionate and butyrate are …

Interaction between gut microbiota and sex hormones and their relation to sexual dimorphism in metabolic diseases

JA Santos-Marcos, M Mora-Ortiz… - Biology of sex …, 2023 - Springer
Metabolic diseases, such as obesity, metabolic syndrome (MetS) and type 2 diabetes (T2D),
are now a widespread pandemic in the developed world. These pathologies show sex …

Nutritional regulation of microbiota-derived metabolites: Implications for immunity and inflammation

M Arifuzzaman, N Collins, CJ Guo, D Artis - Immunity, 2024 - cell.com
Nutrition profoundly shapes immunity and inflammation across the lifespan of mammals,
from pre-and post-natal periods to later life. Emerging insights into diet-microbiota …

Dietary fructose-induced gut dysbiosis promotes mouse hippocampal neuroinflammation: a benefit of short-chain fatty acids

JM Li, R Yu, LP Zhang, SY Wen, SJ Wang, XY Zhang… - Microbiome, 2019 - Springer
Background Western-style diets arouse neuroinflammation and impair emotional and
cognitive behavior in humans and animals. Our previous study showed that a high-fructose …

β-glucans and cholesterol

P Sima, L Vannucci, V Vetvicka - … journal of molecular …, 2018 - spandidos-publications.com
Hypercholesterolemia is one of primary risk factors of cardiovascular disease, together with
metabolic syndrome, hypertension and diabetes. Although progress has been made, the …