Cellular plasma membranes are laterally heterogeneous, featuring a variety of distinct
subcompartments that differ in their biophysical properties and composition. A large number …

Cells are constantly submitted to external mechanical stresses, which they must withstand
and respond to. By forming a physical boundary between cells and their environment that is …

G-protein-coupled receptors (GPCRs) mediate many critical physiological processes. Their
spatial organization in plasma membrane (PM) domains is believed to encode signaling …

Clathrin-mediated endocytosis (CME) involves nanoscale bending and inward budding of
the plasma membrane, by which cells regulate both the distribution of membrane proteins …

Transmembrane nanostructures like ion channels and transporters perform key biological
functions by controlling flow of molecules across lipid bilayers. Much work has gone into …

The importance of curvature as a structural feature of biological membranes has been
recognized for many years and has fascinated scientists from a wide range of different …

To execute their many vital functions, cell membranes are highly organized. Here, we review
how membrane structure shapes signal transduction across membranes. Recent …

The lipid post‐translational modification S‐palmitoylation is a vast developing field, with the
modification itself and the enzymes that catalyse the reversible reaction implicated in a …

The plasma membrane is of central importance for defining the closed volume of cells in
contradistinction to the extracellular environment. The plasma membrane not only serves as …

Synaptotagmin-11 (Syt11) is a vesicle-trafficking protein that is linked genetically to
Parkinson's disease (PD). Likewise, the protein α-synuclein regulates vesicle trafficking, and …