Liver injuries and diseases are serious health problems worldwide. Various factors, such as
chemical pollutants, drugs, and alcohol, could induce liver injuries. Liver diseases involve a …

Fibrosis is a common occurrence following organ injury and failure. To date, there is no
effective treatment for this condition. Melatonin targets numerous molecular pathways, a …

Oxidative stress and energy imbalance strongly correlate in neurodegenerative diseases.
Repeated concussion is becoming a serious public health issue with uncontrollable adverse …

It is believed that oxidative stress is a key causing factor of liver damage induced by a variety
of agents, and it is a major contributing factor in almost all conditions compromising liver …

Abstract Benzo (a) pyrene (BaP), an important environmental pollutant, is produced as the
result of incomplete combustion of organic materials in many industries and food cooking …

The liver is composed of hepatocytes, cholangiocytes, Kupffer cells, sinusoidal endothelial
cells, hepatic stellate cells (HSCs) and dendritic cells; all these functional and interstitial …

We investigated the protective mechanisms of melatonin (MLT) associated with necroptosis
signaling and damage-associated molecular patterns, which are mediated by the activation …

Arsenic (As), a metalloid chemical element, is classified as heavy metal. Previous studies
proposed that As induces vascular toxicity by inducing autophagy, apoptosis, and oxidative …

Melatonin, the hormone of darkness and messenger of the photoperiod, is also well known
to exhibit strong direct and indirect antioxidant properties. Melatonin has previously been …

This work was undertaken to investigate whether treatment with melatonin prevents
oxidative stress and changes in the expression and activity of factor erythroid 2‐related …