Extracellular vesicles in liquid biopsies as biomarkers for solid tumors

B Irmer, S Chandrabalan, L Maas, A Bleckmann… - Cancers, 2023 - mdpi.com
Simple Summary During the past decade, liquid biopsy-related publications have increased
exponentially, demonstrating the great potential of screening body fluids for diagnosis …

Pioneer role of extracellular vesicles as modulators of cancer initiation in progression, drug therapy, and vaccine prospects

S Jahan, S Mukherjee, S Ali, U Bhardwaj… - Cells, 2022 - mdpi.com
Cancer is one of the leading diseases, causing deaths worldwide. Nearly 10 million deaths
were reported in 2020 due to cancer alone. Several factors are involved in cancer …

exoRBase 2.0: an atlas of mRNA, lncRNA and circRNA in extracellular vesicles from human biofluids

H Lai, Y Li, H Zhang, J Hu, J Liao, Y Su… - Nucleic acids …, 2022 - academic.oup.com
Extracellular vesicles (EVs) are small membranous vesicles that contain an abundant cargo
of different RNA species with specialized functions and clinical implications. Here, we …

Isolation of extracellular vesicles from microalgae: a renewable and scalable bioprocess

A Paterna, E Rao, G Adamo, S Raccosta… - … in Bioengineering and …, 2022 - frontiersin.org
Extracellular vesicles (EVs) play a crucial role as potent signal transducers among cells, with
the potential to operate cross-species and cross-kingdom communication. Nanoalgosomes …

Multifunctional targetable liposomal drug delivery system in the management of leukemia: Potential, opportunities, and emerging strategies

E Pardhi, R Yadav, A Chaurasiya, J Madan, SK Guru… - Life Sciences, 2023 - Elsevier
The concern impeding the success of chemotherapy in leukemia treatment is descending
efficacy of drugs because of multiple drug resistance (MDR). The previous failure of …

Diagnostic role of extracellular vesicles in cancer: a comprehensive systematic review and meta-analysis

SY Liu, Y Liao, H Hosseinifard, S Imani… - Frontiers in Cell and …, 2021 - frontiersin.org
Background: Cancer-derived extracellular vesicles (EVs) are regarded to have significant
function in most steps during cancer progression. This meta-analysis aims to investigate the …

Urinary extracellular vesicles: uncovering the basis of the pathological processes in kidney-related diseases

G Cricrì, L Bellucci, G Montini, F Collino - International Journal of …, 2021 - mdpi.com
Intercellular communication governs multicellular interactions in complex organisms. A
variety of mechanisms exist through which cells can communicate, eg, cell-cell contact, the …

CLL-derived extracellular vesicles impair T-cell activation and foster T-cell exhaustion via multiple immunological checkpoints

M Böttcher, R Böttcher-Loschinski, S Kahlfuss… - Cells, 2022 - mdpi.com
Background: Chronic lymphocytic leukemia (CLL) is characterized by the clonal expansion
of malignant B-cells and multiple immune defects. This leads, among others, to severe …

Extracellular vesicle miRNA predict FDG‐PET status in patients with classical Hodgkin Lymphoma

EEE Drees, MGM Roemer… - Journal of …, 2021 - Wiley Online Library
Minimally‐invasive tools to assess tumour presence and burden may improve clinical
management. FDG‐PET (metabolic) imaging is the current gold standard for interim …

Emerging bone marrow microenvironment-driven mechanisms of drug resistance in acute myeloid leukemia: tangle or chance?

M Ciciarello, G Corradi, D Forte, M Cavo, A Curti - Cancers, 2021 - mdpi.com
Simple Summary Despite high rates of remission obtained with conventional chemotherapy,
the persistence of leukemic cells after treatments, eventually exiting in disease relapse …