Tailoring the Swelling‐Shrinkable Behavior of Hydrogels for Biomedical Applications

W Feng, Z Wang - Advanced Science, 2023 - Wiley Online Library
Hydrogels with tailor‐made swelling‐shrinkable properties have aroused considerable
interest in numerous biomedical domains. For example, as swelling is a key issue for blood …

Bioinspired gradient scaffolds for osteochondral tissue engineering

Y Peng, Y Zhuang, Y Liu, H Le, D Li, M Zhang… - …, 2023 - Wiley Online Library
Repairing articular osteochondral defects present considerable challenges in self‐repair
due to the complex tissue structure and low proliferation of chondrocytes. Conventional …

Bioinspired hydrogels as platforms for life-science applications: Challenges and opportunities

M Bercea - Polymers, 2022 - mdpi.com
Hydrogels, as interconnected networks (polymer mesh; physically, chemically, or dynamic
crosslinked networks) incorporating a high amount of water, present structural …

Tailoring biomaterials for biomimetic organs-on-chips

L Sun, F Bian, D Xu, Y Luo, Y Wang, Y Zhao - Materials Horizons, 2023 - pubs.rsc.org
Organs-on-chips are microengineered microfluidic living cell culture devices with
continuously perfused chambers penetrating to cells. By mimicking the biological features of …

Dual-network DNA–silk fibroin hydrogels with controllable surface rigidity for regulating chondrogenic differentiation

Z Zhou, P Song, Y Wu, M Wang, C Shen, Z Ma… - Materials …, 2024 - pubs.rsc.org
Osteoarthritis (OA) is a common joint disease known for cartilage degeneration, leading to a
substantial burden on individuals and society due to its high disability rate. However, current …

3D-biofabricated chondrocyte-laden decellularized extracellular matrix-contained gelatin methacrylate auxetic scaffolds under cyclic tensile stimulation for cartilage …

YW Chen, YH Lin, TL Lin, KXA Lee, MH Yu… - Biofabrication, 2023 - iopscience.iop.org
Abstract Three-dimensional (3D) hydrogel constructs can mimic features of the extracellular
matrix (ECM) and have tailorable physicochemical properties to support and maintain the …

Advanced injectable hydrogels for cartilage tissue engineering

S Zhu, Y Li, Z He, L Ji, W Zhang, Y Tong… - … in bioengineering and …, 2022 - frontiersin.org
The rapid development of tissue engineering makes it an effective strategy for repairing
cartilage defects. The significant advantages of injectable hydrogels for cartilage injury …

Converse modulation of Wnt/β-catenin signaling during expansion and differentiation phases of Infrapatellar fat pad-derived MSCs for improved engineering of …

A Mahajan, MA Nengroo, D Datta, DS Katti - Biomaterials, 2023 - Elsevier
Mesenchymal stem cells (MSCs) are potential candidates in cell-based therapy for cartilage
repair and regeneration. However, during chondrogenic differentiation, MSCs undergo …

Dynamic hydrogels with viscoelasticity and tunable stiffness for the regulation of cell behavior and fate

Y Zhang, Z Wang, Q Sun, Q Li, S Li, X Li - Materials, 2023 - mdpi.com
The extracellular matrix (ECM) of natural cells typically exhibits dynamic mechanical
properties (viscoelasticity and dynamic stiffness). The viscoelasticity and dynamic stiffness of …

Injectable hydrogels as promising in situ therapeutic platform for cartilage tissue engineering

R Cai, Y Shan, F Du, Z Miao, L Zhu, L Hang… - International Journal of …, 2024 - Elsevier
Injectable hydrogels are gaining prominence as a biocompatible, minimally invasive, and
adaptable platform for cartilage tissue engineering. Commencing with their synthesis, this …