Background Despite lithium being the most efficacious treatment for bipolar disorder, its use
has been decreasing at least in part due to concerns about its potential to cause significant …

Lithium is the first line therapy of bipolar mood disorder. Lithium-induced nephrogenic
diabetes insipidus (Li-NDI) and lithium nephropathy (Li-NP, ie, renal insufficiency) are …

Importance Among patients with bipolar disorder, discordant findings have been published
on the nephrotoxic effects of lithium therapy. Objective To quantify absolute and relative risks …

Background Concerns about potential adverse effects of long-term exposure to lithium as a
mood-stabilizing treatment notably include altered renal function. However, the incidence of …

Abstract Background and Objective Psychotropic drugs are a heterogenous group of
treatments prescribed for many psychiatric disorders, often for long periods. Their effects on …

Background For more than 40 years, the long-term effect of lithium maintenance therapy on
renal function has been debated. We aimed to assess the effect of lithium maintenance …

Lithium preparations have been successfully used to treat bipolar disorder (BD), and remain
the best established long-term treatment for the disorder. In fact, lithium is a cornerstone of …

Initial evidence suggests that lithium might affect life expectancy and the risk for different
disease conditions, but most studies were conducted in patients on lithium medication. Little …

Introduction Lithium augmentation (LA) of antidepressants is a first‐line therapy option for
treatment‐resistant depression (TRD). Nevertheless, it is rarely used in geriatric patients …

Despite the progress made in treating bipolar and unipolar affective disorders, lithium
carbonate is still a common drug in psychiatric practice. Lithium‐related renal side effects …